Hao Y Z
Dept. Radiodiagnosis, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing.
Zhonghua Zhong Liu Za Zhi. 1991 Sep;13(5):362-5.
The splenic metastasis of malignant diseases is uncommon. The relative paucity of this condition is thought to be due to the property of the spleen as an organ of immunity and the sharp angle of the splenic artery at its origin from the coeliac axis making it difficult for the tumor emboli to enter the spleen. The primary sites of 15 splenic metastases were: 7 (43%) ovarian tumors, and 8 (57%) others. All 15 patients had been repeatedly examined by ultrasonography. 6 patients were shown to give hyperechoic, 6 hypoechoic and 3 nonechoic findings. 10 patients had been examined by CT scan. Except one splenic metastasis of malignant teratoma with calcification, reduced density lesions were seen on ordinary and enhanced CT scans in all. We are of the opinion ther the most common route of splenic metastasis is hematogenous or direct seeding. The high incidence of splenic metastasis in gynecologic tumors may be related to their particular biologic behavior of being prone to direct seeding.
恶性疾病的脾转移并不常见。这种情况相对较少被认为是由于脾脏作为免疫器官的特性以及脾动脉从腹腔干起始处的锐角，使得肿瘤栓子难以进入脾脏。15例脾转移的原发部位为：7例（43%）卵巢肿瘤，8例（57%）其他肿瘤。所有15例患者均多次接受超声检查。6例显示为高回声，6例为低回声，3例为无回声。10例患者接受了CT扫描。除1例恶性畸胎瘤脾转移伴钙化外，所有患者在普通CT扫描和增强CT扫描中均可见密度减低病变。我们认为脾转移最常见的途径是血行转移或直接种植。妇科肿瘤中脾转移的高发生率可能与其易于直接种植的特殊生物学行为有关。
