Korcum Aylin Fidan, Aksu Gamze, Bozcuk Hakan, Pestereli Elif, Simsek Tayup
Department of Radiation Oncology, Akdeniz University, School of Medicine, 07070, Antalya, Turkey.
Arch Gynecol Obstet. 2008 Apr;277(4):367-70. doi: 10.1007/s00404-007-0463-9. Epub 2007 Sep 9.
Small cell carcinoma of the uterine cervix accounts for 1-3% of all cervix cancers. It is an aggressive disease with a poor prognosis. To date, no effective treatment protocol has been determined. Surgery, radiotherapy, and chemotherapy have been used either alone or in combination. Recent data suggests that survival in patients with early staged small cell carcinoma of the cervix is better with surgery combined with chemo-radiotherapy. Here, we presented two patients with stage IB1 small cell carcinoma of the uterine cervix. For both patients, definitive surgery was performed with pelvic and para-aortic lymphadenectomy. Subsequently, they were treated with pelvic external radiotherapy and high-dose-rate intracavitary brachytherapy with concurrent cisplatin based chemotherapy. They were alive with no evidence of disease at 91 and 65 months, respectively.
子宫颈小细胞癌占所有宫颈癌的1%-3%。它是一种侵袭性疾病，预后较差。迄今为止，尚未确定有效的治疗方案。手术、放疗和化疗已单独或联合使用。最近的数据表明，早期子宫颈小细胞癌患者采用手术联合放化疗的生存率更高。在此，我们报告了两名IB1期子宫颈小细胞癌患者。两名患者均接受了根治性手术及盆腔和腹主动脉旁淋巴结清扫术。随后，他们接受了盆腔外照射放疗和高剂量率腔内近距离放疗，并同时进行基于顺铂的化疗。他们分别在91个月和65个月时存活且无疾病证据。
