Marinho H A, Shrimpton R, Giugliano R, Burini R C
Instituto Nacional de Pesquisas da Amazônia (INPA), Manaus, Brazil.
Eur J Clin Nutr. 1991 Nov;45(11):539-44.
A sample of 471 pre-school children who frequented schools and crêches in a poor district of Manaus (Amazonas), Brazil, were randomly submitted to faecal parasitological tests. Two-hundred-and-forty children from both sexes between the ages of 3 and 7 years with Ascaris lumbricoides and/or Giardia lamblia were selected. The objective of the study was to determine the possible influence of these two intestinal parasites and vitamin A and/or zinc supplementation on the serum retinol levels of primary school children. The children were submitted to clinical and anthropometric examinations, dietary interviews and biochemical examinations of retinol and carotene in the serum and of zinc in the hair. The parasitic incidence was 85.0% and about 54% of the children were polyparasitic. During the pretreatment phase, the retinol and carotene serum levels were 36% and 57%, respectively, below the normal levels. Using the Waterlow classification, the anthropometric analyses revealed that 88% of the children showed normal growth. A significant effect was observed of the anti-parasitic medicine on the serum retinol levels.
在巴西马瑙斯（亚马孙州）一个贫困地区的学校和托儿所里，随机抽取了471名学龄前儿童进行粪便寄生虫学检测。从3至7岁的儿童中挑选出240名感染蛔虫和/或贾第鞭毛虫的男女儿童。本研究的目的是确定这两种肠道寄生虫以及维生素A和/或锌补充剂对小学生血清视黄醇水平的可能影响。对这些儿童进行了临床和人体测量检查、饮食访谈以及血清视黄醇和胡萝卜素以及头发中锌的生化检查。寄生虫感染率为85.0%，约54%的儿童为多重寄生虫感染。在预处理阶段，血清视黄醇和胡萝卜素水平分别比正常水平低36%和57%。使用沃特洛分类法进行人体测量分析显示，88%的儿童生长正常。观察到抗寄生虫药物对血清视黄醇水平有显著影响。
