非洛地平对哮喘患者组胺和腺苷诱发支气管收缩的作用。
Effect of felodipine on histamine and adenosine induced bronchoconstriction in patients with asthma.
作者信息
Ghosh S K, Rafferty P
机构信息
Department of Respiratory Medicine, Western Infirmary, Glasgow, Scotland, UK.
出版信息
Eur J Clin Pharmacol. 1991;41(1):73-4. doi: 10.1007/BF00280111.
PMID:1782982
Abstract
The effect of felodipine, a new selective calcium antagonist, was assessed on histamine and adenosine monophosphate (AMP) induced bronchoconstriction in 9 mild atopic asthmatics. Felodipine did not alter the baseline FEV1, but showed a small significant inhibitory effect upon histamine and AMP induced bronchoconstriction.
摘要
对9名轻度特应性哮喘患者，评估了新型选择性钙拮抗剂非洛地平对组胺和单磷酸腺苷（AMP）诱导的支气管收缩的作用。非洛地平未改变基础第一秒用力呼气容积（FEV1），但对组胺和AMP诱导的支气管收缩显示出小的显著抑制作用。
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