• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

非洛地平对哮喘患者组胺和腺苷诱发支气管收缩的作用。

Effect of felodipine on histamine and adenosine induced bronchoconstriction in patients with asthma.

作者信息

Ghosh S K, Rafferty P

机构信息

Department of Respiratory Medicine, Western Infirmary, Glasgow, Scotland, UK.

出版信息

Eur J Clin Pharmacol. 1991;41(1):73-4. doi: 10.1007/BF00280111.

DOI:10.1007/BF00280111
PMID:1782982
Abstract

The effect of felodipine, a new selective calcium antagonist, was assessed on histamine and adenosine monophosphate (AMP) induced bronchoconstriction in 9 mild atopic asthmatics. Felodipine did not alter the baseline FEV1, but showed a small significant inhibitory effect upon histamine and AMP induced bronchoconstriction.

摘要

对9名轻度特应性哮喘患者，评估了新型选择性钙拮抗剂非洛地平对组胺和单磷酸腺苷（AMP）诱导的支气管收缩的作用。非洛地平未改变基础第一秒用力呼气容积（FEV1），但对组胺和AMP诱导的支气管收缩显示出小的显著抑制作用。

相似文献

1
Effect of felodipine on histamine and adenosine induced bronchoconstriction in patients with asthma.非洛地平对哮喘患者组胺和腺苷诱发支气管收缩的作用。
Eur J Clin Pharmacol. 1991;41(1):73-4. doi: 10.1007/BF00280111.
2
Comparison of salmeterol and albuterol-induced bronchoprotection against adenosine monophosphate and histamine in mild asthma.沙美特罗与沙丁胺醇对轻度哮喘患者针对单磷酸腺苷和组胺诱导的支气管保护作用的比较。
Am J Respir Crit Care Med. 1997 Dec;156(6):1731-7. doi: 10.1164/ajrccm.156.6.9703047.
3
Inhaled lysine acetylsalicylate (L-ASA) attenuates the bronchoconstrictor response to adenosine 5'-monophosphate (AMP) in asthmatic subjects.吸入赖氨酸乙酰水杨酸酯（L-ASA）可减轻哮喘患者对5'-单磷酸腺苷（AMP）的支气管收缩反应。
Eur Respir J. 1995 Jun;8(6):905-12.
4
Repeated inhalation of bradykinin attenuates adenosine 5'-monophosphate (AMP) induced bronchoconstriction in asthmatic airways.反复吸入缓激肽可减轻哮喘气道中5'-单磷酸腺苷（AMP）诱导的支气管收缩。
Eur Respir J. 1992 Jun;5(6):700-6.
5
The contribution of histamine to immediate bronchoconstriction provoked by inhaled allergen and adenosine 5' monophosphate in atopic asthma.
Am Rev Respir Dis. 1987 Aug;136(2):369-73. doi: 10.1164/ajrccm/136.2.369.
6
The relative contributions of histamine and prostanoids to bronchoconstriction provoked by isocapnic hyperventilation in asthma.组胺和前列腺素对哮喘患者等碳酸血症性过度通气诱发支气管收缩的相对作用。
Eur Respir J. 1992 Mar;5(3):323-30.
7
Bronchoprotection by salmeterol: cell stabilization or functional antagonism? Comparative effects on histamine- and AMP-induced bronchoconstriction.沙美特罗的支气管保护作用：细胞稳定还是功能拮抗？对组胺和AMP诱导的支气管收缩的比较影响。
Eur Respir J. 1994 Nov;7(11):1973-7.
8
Adenosine 5'-monophosphate in asthma: gas exchange and sputum cellular responses.哮喘中的5'-单磷酸腺苷：气体交换与痰液细胞反应
Eur Respir J. 2008 Jun;31(6):1205-12. doi: 10.1183/09031936.00116207. Epub 2008 Feb 20.
9
Adenosine receptor subtypes in the airways responses to 5'-adenosine monophosphate inhalation of sensitized guinea-pigs.气道中腺苷受体亚型对致敏豚鼠吸入5'-单磷酸腺苷的反应
Clin Exp Allergy. 2008 Sep;38(9):1536-47. doi: 10.1111/j.1365-2222.2008.03034.x. Epub 2008 Jul 18.
10
The influence of refractoriness to adenosine 5'-monophosphate on allergen-provoked bronchoconstriction in asthma.5'-单磷酸腺苷难治性对哮喘中变应原诱发的支气管收缩的影响。
Am Rev Respir Dis. 1989 Aug;140(2):321-6. doi: 10.1164/ajrccm/140.2.321.

引用本文的文献

1
Felodipine. A review of the pharmacology and therapeutic use of the extended release formulation in older patients.非洛地平。老年患者缓释制剂的药理学与治疗应用综述。
Drugs Aging. 1992 Sep-Oct;2(5):374-88. doi: 10.2165/00002512-199202050-00002.
2
Felodipine. A review of the pharmacology and therapeutic use of the extended release formulation in cardiovascular disorders.非洛地平。缓释制剂在心血管疾病中的药理学及治疗应用综述。
Drugs. 1992 Aug;44(2):251-77. doi: 10.2165/00003495-199244020-00008.

本文引用的文献

1
The effect of verapamil on histamine and methacholine-induced bronchoconstriction.维拉帕米对组胺和乙酰甲胆碱诱导的支气管收缩的影响。
Clin Allergy. 1981 Sep;11(5):441-7. doi: 10.1111/j.1365-2222.1981.tb01617.x.
2
Effect of calcium antagonists on allergen-induced asthma.钙拮抗剂对变应原诱导哮喘的影响。
Clin Allergy. 1982 Nov;12(6):595-600. doi: 10.1111/j.1365-2222.1982.tb02558.x.
3
The effect of inhaled verapamil on allergen-induced bronchoconstriction.吸入维拉帕米对变应原诱导的支气管收缩的影响。
Clin Allergy. 1983 Mar;13(2):119-22. doi: 10.1111/j.1365-2222.1983.tb02578.x.
4
Effect of nifedipine on histamine reactivity in asthma.硝苯地平对哮喘患者组胺反应性的影响。
Br Med J (Clin Res Ed). 1982 Jun 26;284(6333):1916. doi: 10.1136/bmj.284.6333.1916.
5
Effect of nifedipine on bronchomotor tone and histamine reactivity in asthma.硝苯地平对哮喘患者支气管运动张力和组胺反应性的影响。
Br Med J (Clin Res Ed). 1981 Aug 1;283(6287):348. doi: 10.1136/bmj.283.6287.348.
6
Inhaled adenosine and guanosine on airway resistance in normal and asthmatic subjects.吸入腺苷和鸟苷对正常人和哮喘患者气道阻力的影响。
Br J Clin Pharmacol. 1983 Feb;15(2):161-5. doi: 10.1111/j.1365-2125.1983.tb01481.x.
7
Effects of nifedipine on antigen-induced bronchoconstriction.硝苯地平对抗原诱导的支气管收缩的作用。
Am Rev Respir Dis. 1983 May;127(5):549-53. doi: 10.1164/arrd.1983.127.5.549.
8
Adenosine inhibits and potentiates IgE-dependent histamine release from human basophils by an A2-receptor mediated mechanism.腺苷通过A2受体介导的机制抑制并增强人嗜碱性粒细胞中IgE依赖的组胺释放。
Br J Pharmacol. 1983 Dec;80(4):719-26. doi: 10.1111/j.1476-5381.1983.tb10063.x.
9
The contribution of histamine to immediate bronchoconstriction provoked by inhaled allergen and adenosine 5' monophosphate in atopic asthma.
Am Rev Respir Dis. 1987 Aug;136(2):369-73. doi: 10.1164/ajrccm/136.2.369.
10
Clinical pharmacokinetics of felodipine. A summary.非洛地平的临床药代动力学。综述。
Drugs. 1987;34 Suppl 3:16-27. doi: 10.2165/00003495-198700343-00005.