Seow W K
University of Queensland Dental School, Brisbane, Australia.
ASDC J Dent Child. 1991 Nov-Dec;58(6):441-52.
Clinical significance of enamel hypoplasia includes poor esthetics, tooth sensitivity, malocclusion and predisposition to dental caries. It may provide diagnostic clues as to genetic influences and systemic diseases, as well as to any trauma during the span of dental development. These systemic factors include birth trauma, infections, nutritional disorders, metabolic diseases, and exposures to chemicals such as tetracycline, lead, and fluoride. Inherited types form a relatively small component overall, including genetic abnormalities of enamel formation, or dental features of many inherited diseases or dysmorphic syndromes. Developmental enamel defects range in prevalence from 4 percent to 60 percent, depending on the criteria and the population studied. It is likely that many of these individual factors may in fact act through a central mechanism: mineral deficiency.
釉质发育不全的临床意义包括美观性差、牙齿敏感、错牙合畸形以及易患龋齿。它可能为遗传影响、全身性疾病以及牙齿发育期间的任何创伤提供诊断线索。这些全身性因素包括出生时的创伤、感染、营养失调、代谢疾病以及接触四环素、铅和氟化物等化学物质。遗传性类型总体上占比较小，包括釉质形成的基因异常，或许多遗传性疾病或畸形综合征的牙齿特征。发育性釉质缺陷的患病率在4%至60%之间，具体取决于所研究的标准和人群。实际上，许多这些个体因素可能通过一个核心机制起作用：矿物质缺乏。
