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[Radiation sterilization of drugs].

作者信息

Tilquin B

机构信息

CHAM/72.30, Unité d'Analyse Chimique, et Physico-Chimique des Médicaments, Tour Ehrlich, Bruxelles, Belgique.

出版信息

J Pharm Belg. 1991 Nov-Dec;46(6):396-8.

PMID:1783974
Abstract

Radiation sterilization can be carried out on the final packaged drug, is applicable to heat or ethylene oxyde sensitive compounds and is eased in control and monitoring. Most of the drugs seem to be not affected by irradiation, however it is necessary to be established that any traces of radiolytic products formed are not toxic. E.S.R. is a good detection method for irradiated drug.

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