Tilquin B
CHAM/72.30, Unité d'Analyse Chimique, et Physico-Chimique des Médicaments, Tour Ehrlich, Bruxelles, Belgique.
J Pharm Belg. 1991 Nov-Dec;46(6):396-8.
Radiation sterilization can be carried out on the final packaged drug, is applicable to heat or ethylene oxyde sensitive compounds and is eased in control and monitoring. Most of the drugs seem to be not affected by irradiation, however it is necessary to be established that any traces of radiolytic products formed are not toxic. E.S.R. is a good detection method for irradiated drug.
辐射灭菌可在最终包装好的药品上进行,适用于对热或环氧乙烷敏感的化合物,且易于控制和监测。大多数药物似乎不受辐照影响,然而有必要确定所形成的任何微量辐射分解产物无毒。电子自旋共振是检测辐照药物的一种好方法。