Taki J, Nakajima K, Bunko H, Taniguchi M, Kawasuji M, Tonami N, Hisada K
Department of Nuclear Medicine, Kanazawa University School of Medicine.
Kaku Igaku. 1991 Dec;28(12):1423-8.
Twenty-four-hour delayed imaging after stress thallium-201 scintigraphy was assessed for more accurate detection of viable myocardium. Thirty-two patients with coronary artery disease who showed fixed perfusion abnormality (FPA) at 3 hr imaging after stress Tl study were evaluated with 24 hr delayed imaging. Of 37 areas with FPA, 19 areas (51%) showed redistribution (RD) at 24 hr imaging. After successful coronary artery bypass grafting (n = 19) or transluminal coronary angioplasty (n = 3), stress Tl scintigraphy was performed. Of 13 areas with RD at 24 hr imaging, 12 revealed improvement of Tl uptake after revascularization. On the other hand, of 12 areas with FPA until 24 hr, 8 showed no improvement. In conclusion, conventional stress Tl-201 scintigraphy underestimates myocardial viability, and additional 24 hr imaging permits more accurate assessment of myocardial viability.
对负荷铊-201闪烁显像后24小时延迟显像进行评估,以更准确地检测存活心肌。对32例在负荷铊研究后3小时显像显示为固定灌注异常(FPA)的冠心病患者进行了24小时延迟显像评估。在37个存在FPA的区域中,19个区域(51%)在24小时显像时显示有再分布(RD)。在成功进行冠状动脉搭桥术(n = 19)或经皮腔内冠状动脉成形术(n = 3)后,进行了负荷铊闪烁显像。在24小时显像时存在RD的13个区域中,12个区域在血运重建后铊摄取得到改善。另一方面,在直至24小时都存在FPA的12个区域中,8个区域没有改善。总之,传统的负荷铊-201闪烁显像低估了心肌存活性,额外的24小时显像可更准确地评估心肌存活性。