• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Rat hepatic P450IIA and P450IIC subfamily expression using catalytic, immunochemical, and molecular probes.

作者信息

Waxman D J

出版信息

Methods Enzymol. 1991;206:249-67. doi: 10.1016/0076-6879(91)06095-k.

DOI:10.1016/0076-6879(91)06095-k
PMID:1784212
Abstract
摘要

相似文献

1
Rat hepatic P450IIA and P450IIC subfamily expression using catalytic, immunochemical, and molecular probes.
Methods Enzymol. 1991;206:249-67. doi: 10.1016/0076-6879(91)06095-k.
2
Effect of rociverine on P450-dependent monooxygenases and its N-deethylation metabolism in rat liver microsomes.罗西维林对大鼠肝微粒体中细胞色素P450依赖性单加氧酶及其N-脱乙基代谢的影响。
Biochem Pharmacol. 1993 Mar 9;45(5):1097-105. doi: 10.1016/0006-2952(93)90254-t.
3
Cloning and expression of complementary DNAs for multiple members of the human cytochrome P450IIC subfamily.人细胞色素P450IIC亚家族多个成员互补DNA的克隆与表达
Biochemistry. 1991 Apr 2;30(13):3247-55. doi: 10.1021/bi00227a012.
4
Identification of the fetal liver cytochrome CYP3A7 in human endometrium and placenta.人子宫内膜和胎盘中胎儿肝脏细胞色素CYP3A7的鉴定。
J Clin Invest. 1993 Aug;92(2):1018-24. doi: 10.1172/JCI116607.
5
P450-catalyzed steroid hydroxylation: assay and product identification by thin-layer chromatography.细胞色素P450催化的类固醇羟基化作用：通过薄层色谱法进行测定和产物鉴定
Methods Enzymol. 1991;206:462-76. doi: 10.1016/0076-6879(91)06115-j.
6
Effects of 17beta-estradiol and testosterone on hepatic mRNA/protein levels and catalytic activities of CYP2M1, CYP2K1, and CYP3A27 in rainbow trout (Oncorhynchus mykiss).17β-雌二醇和睾酮对虹鳟（Oncorhynchus mykiss）肝脏中CYP2M1、CYP2K1和CYP3A27的mRNA/蛋白质水平及催化活性的影响
Toxicol Appl Pharmacol. 2000 Oct 15;168(2):91-101. doi: 10.1006/taap.1999.9016.
7
Differences in the cytochrome P-450 isoenzymes involved in the 2-hydroxylation of oestradiol and 17 alpha-ethinyloestradiol. Relative activities of rat and human liver enzymes.参与雌二醇和17α-乙炔雌二醇2-羟基化过程的细胞色素P-450同工酶的差异。大鼠和人肝脏酶的相对活性。
Biochem J. 1990 Apr 1;267(1):221-6. doi: 10.1042/bj2670221.
8
Purification of two cytochrome P450 isozymes related to CYP2A and CYP3A gene families from monkey (baboon, Papio papio) liver microsomes. Cross reactivity with human forms.从猴（狒狒，巴氏狒狒）肝微粒体中纯化与CYP2A和CYP3A基因家族相关的两种细胞色素P450同工酶。与人源形式的交叉反应性。
Eur J Biochem. 1992 Mar 1;204(2):641-8. doi: 10.1111/j.1432-1033.1992.tb16677.x.
9
Modulation of the expression on constitutive rat hepatic cytochrome P450 isozymes by 5-fluorouracil.
Can J Physiol Pharmacol. 1996 Feb;74(2):150-6.
10
Identification and localization of cytochromes P450 expressed in brain.
Methods Enzymol. 1991;206:631-40. doi: 10.1016/0076-6879(91)06133-n.

引用本文的文献

1
Permanent uncoupling of male-specific CYP2C11 transcription/translation by perinatal glutamate.围产期谷氨酸导致雄性特异性细胞色素P450 2C11转录/翻译的永久性解偶联。
Toxicol Appl Pharmacol. 2015 Apr 1;284(1):79-91. doi: 10.1016/j.taap.2015.02.009. Epub 2015 Feb 16.
2
Growth hormone-independent suppression of growth hormone-dependent female isoforms of cytochrome P450 by the somatostatin analog octreotide.生长抑素类似物奥曲肽对生长激素依赖性细胞色素 P450 同工型的生长激素非依赖性抑制。
Eur J Pharmacol. 2013 Sep 5;715(1-3):256-61. doi: 10.1016/j.ejphar.2013.05.013. Epub 2013 May 21.
3
Noncanonical suppression of GH-dependent isoforms of cytochrome P450 by the somatostatin analog octreotide.
生长抑素类似物奥曲肽对 GH 依赖性细胞色素 P450 同工型的非规范抑制作用。
J Endocrinol. 2013 Jan 2;216(1):87-97. doi: 10.1530/JOE-12-0255. Print 2013 Jan.
4
Intrasplenic transplantation of isolated adult rat hepatocytes: sex-reversal and/or suppression of the major constituent isoforms of cytochrome P450.成年大鼠分离肝细胞的脾内移植：细胞色素P450主要组成亚型的性别逆转和/或抑制
Toxicol Pathol. 2012;40(1):83-92. doi: 10.1177/0192623311425061. Epub 2011 Nov 14.
5
Growth hormone (GH) secretion, GH-dependent gene expression, and sexually dimorphic body growth in young rats with chronic renal failure.慢性肾功能衰竭幼鼠的生长激素（GH）分泌、GH依赖性基因表达及两性体型生长
Endocrine. 2008 Jun;33(3):323-30. doi: 10.1007/s12020-008-9094-6.
6
Sex-dependent expression of CYP2C11 in spleen, thymus and bone marrow regulated by growth hormone.生长激素调节脾脏、胸腺和骨髓中CYP2C11的性别依赖性表达。
Biochem Pharmacol. 2007 Nov 15;74(10):1476-84. doi: 10.1016/j.bcp.2007.07.035. Epub 2007 Jul 31.
7
Interpulse growth hormone secretion in the episodic plasma profile causes the sex reversal of cytochrome P450s in senescent male rats.间歇性血浆中生长激素分泌导致衰老雄性大鼠细胞色素P450s的性别逆转。
Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):15224-8. doi: 10.1073/pnas.2434273100. Epub 2003 Nov 24.
8
The kidney cytochrome P-450 2C23 arachidonic acid epoxygenase is upregulated during dietary salt loading.肾脏细胞色素P-450 2C23花生四烯酸环氧化酶在饮食盐负荷增加时上调。
J Clin Invest. 1999 Sep;104(6):751-60. doi: 10.1172/JCI7013.
9
The lithocholic acid 6 beta-hydroxylase cytochrome P-450, CYP 3A10, is an active catalyst of steroid-hormone 6 beta-hydroxylation.石胆酸6β-羟化酶细胞色素P-450，即CYP 3A10，是类固醇激素6β-羟化的活性催化剂。
Biochem J. 1993 Apr 15;291 ( Pt 2)(Pt 2):429-33. doi: 10.1042/bj2910429.
10
Altered expression of cytochrome P-450 mRNAs, and potentially of other transcripts encoding key hepatic functions, are triggered during the isolation of rat hepatocytes.在大鼠肝细胞分离过程中，细胞色素P - 450 mRNA以及可能编码关键肝功能的其他转录本的表达会发生改变。
Biochem J. 1993 Feb 1;289 ( Pt 3)(Pt 3):621-4. doi: 10.1042/bj2890621.