McIlwain H
Department of Pharmacology, Birmingham University Medical School, U.K.
Neurochem Res. 1991 Sep;16(9):1079-84. doi: 10.1007/BF00965854.
Neurochemistry in the 1850s was part of comparative animal chemistry, which became incorporated into physiological chemistry. By 1900, the connection with physiological chemistry had largely lapsed or been vehemently repudiated. Growth of biochemistry, especially from the 1920s to 1950s, provided techniques and findings sufficient to reintegrate chemical knowledge of neural systems with neural functioning. Vitamin, coenzyme, respiratory and other metabolic studies made large contributions to this outcome. Regarding mental illness as a social problem and scientific challenge gave impetus and funds to such work, which resulted in major experimental and cognitive progress.
19世纪50年代的神经化学是比较动物化学的一部分,后来被纳入生理化学。到1900年,与生理化学的联系在很大程度上已经中断或遭到强烈否定。生物化学的发展,尤其是从20世纪20年代到50年代,提供了足以将神经系统的化学知识与神经功能重新整合的技术和发现。维生素、辅酶、呼吸及其他代谢研究对此成果贡献巨大。将精神疾病视为一个社会问题和科学挑战,为这类工作提供了动力和资金,从而带来了重大的实验和认知进展。