[Hemodynamic and metabolic disorders in the early period of traumatic disease].

In the article are presented the results of study and treatment of 804 patients with polytrauma. In part of the patients in early period of the traumatic disease have been studied in complex the states of hemodynamics (circulating blood volume, specific peripheral resistance, cardiac index, central venous pressure, arterial pressure, heart rate) and metabolism (total protein, basal metabolism, the level of endogenous nitrogen in urine). On the basis of the obtained data there is proposed the evaluation of the hemodynamics changes, energetic and plastic losses at polytrauma that formed the basis of the pathogenetic therapy ensuring simultaneous correction of the detected disturbances. It allowed the author to reduce the number of unfavourable outcomes (anatomical by 20.9% (p less than 0.05), functional by 20.7% (p less than 0.05), labour by 19.5% (p less than 0.05) and lethality (at the multiple damages by 2.0% (p less than 0.05), at associated craniocerebral injury by 3.0%, at associated trauma of internal organs and locomotor system by 6.0% (p less than 0.05).