Mausbach Brent T, Patterson Thomas L, Rabinowitz Yaron G, Grant Igor, Schulz Richard
Department of Psychiatry, University of California, San Diego, CA 92093-0680, USA.
Health Psychol. 2007 Sep;26(5):539-44. doi: 10.1037/0278-6133.26.5.539.
This study assessed the impact of depressive symptoms and distress from patient problem behaviors on time to developing a diagnosis of cardiovascular disease (CVD) in a sample of 643 dementia family caregivers.
A longitudinal, prospective design was used. Over an 18-month period, caregivers free from a CVD diagnosis at baseline were assessed at 6, 12, and 18-month follow-ups for the onset of CVD.
Days to the onset of CVD was the primary outcome.
Over the length of the study, 32 participants (5%) reported a diagnosis of CVD. After adjusting for sociodemographic and health factors (e.g., high blood pressure, age, smoking history), greater depressive symptoms (p = .040) and distress from patient problem behaviors (p = .034) were significant predictors of time to CVD diagnosis.
This study suggests that increased depressive symptoms and reaction to patient problem behaviors (i.e., distress) may increase caregivers' risk for experiencing negative health outcomes, specifically CVD.
本研究评估了643名痴呆症家庭照料者的抑郁症状及患者问题行为所带来的困扰对心血管疾病（CVD）诊断时间的影响。
采用纵向前瞻性设计。在18个月的时间里，对基线时未被诊断患有CVD的照料者在第6、12和18个月随访时评估CVD的发病情况。
CVD发病天数是主要结局。
在研究期间，32名参与者（5%）报告被诊断患有CVD。在调整了社会人口学和健康因素（如高血压、年龄、吸烟史）后，更严重的抑郁症状（p = 0.040）和患者问题行为所带来的困扰（p = 0.034）是CVD诊断时间的显著预测因素。
本研究表明，抑郁症状增加以及对患者问题行为的反应（即困扰）可能会增加照料者出现负面健康结局的风险，特别是CVD。
