家猫（Felis catus）中CCR2和CCR5之间广泛的基因转换。
Extensive gene conversion between CCR2 and CCR5 in domestic cat (Felis catus).
作者信息
Esteves P J, Abrantes J, van der Loo W
机构信息
CIBIO, Centro de Investigação em Biodiversidade e Recursos Genéticos, Campus Agrário de Vairão, Vairão, Portugal.
出版信息
Int J Immunogenet. 2007 Oct;34(5):321-4. doi: 10.1111/j.1744-313X.2007.00716.x.
Abstract
Homogenization of the CC-motif chemokine receptors CCR2 and CCR5 of cat (Felis catus) is documented and shown to be the outcome of gene conversion within the feline lineage. All regions were concerned, except the three extracellular protein domains (N- and C-tails, and ECL2), suggesting that structural differentiation at these domains could be related to pathogen susceptibility.
摘要
猫（Felis catus）的CC基序趋化因子受体CCR2和CCR5的同质化已被记录，并被证明是猫科谱系内基因转换的结果。除了三个细胞外蛋白质结构域（N端和C端尾巴以及ECL2）外，所有区域都受到影响，这表明这些结构域的结构分化可能与病原体易感性有关。
Zotero 插件