Nakae Hajime, Igarashi Toshiko, Tajimi Kimitaka, Kusano Tomoyuki, Shibata Satoshi, Kume Makoto, Sato Tsutomu, Yamamoto Yuzo
Department of Integrated Medicine, Division of Emergency and Critical Care Medicine, Akita University School of Medicine, Akita, Japan.
Ther Apher Dial. 2007 Oct;11(5):391-5. doi: 10.1111/j.1744-9987.2007.00505.x.
Plasma diafiltration (PDF) (selective plasma filtration with dialysis) is blood purification therapy in which simple plasma exchange is performed using a membrane plasma separator (Evacure EC-2A) while dialysate flows outside of the hollow-fibers. A 74-year old man with hepatorenal syndrome underwent four sessions of PDF and three sessions of HDF. Finally he recovered from hepatorenal syndrome. In this therapy, the levels of total bilirubin, interleukin-18, creatinine, and cystatin C were significantly reduced. On the other hand, there were no significant differences in the total protein and albumin levels before and after PDF. PDF may be one of the most useful blood purification therapies for hepatorenal syndrome in terms of medical economics.
血浆滤过透析（PDF）（选择性血浆滤过与透析）是一种血液净化疗法，即在使用膜式血浆分离器（Evacure EC - 2A）进行单纯血浆置换时，透析液在中空纤维外部流动。一名患有肝肾综合征的74岁男性接受了4次血浆滤过透析和3次高通量透析。最终，他从肝肾综合征中康复。在该治疗中，总胆红素、白细胞介素 - 18、肌酐和胱抑素C水平显著降低。另一方面，血浆滤过透析前后总蛋白和白蛋白水平无显著差异。从医疗经济学角度来看，血浆滤过透析可能是治疗肝肾综合征最有用的血液净化疗法之一。
