Agarwal Sanjay K, Estrada Sylvia, Foster Warren G, Wall L Lewis, Brown Doug, Revis Elaine S, Rodriguez Suzanne
Department of Reproductive Medicine, UCSD School of Medicine, Basic Science Building #5040, 9500 Gilman Drive, La Jolla, California 92093-0633, USA.
Bioethics. 2007 Jun;21(5):263-9. doi: 10.1111/j.1467-8519.2007.00552.x.
The objective of this study was to identify factors motivating women to take part in endometriosis research and to determine if these factors differ for women participating in clinical versus basic science studies.
A consecutive series of 24 women volunteering for participation in endometriosis-related research were asked to indicate, in their own words, why they chose to volunteer. In addition, the women were asked to rate, on a scale of 0 to 10, sixteen potentially motivating factors. The information was gathered in the form of an anonymous self-administered questionnaire.
Strong motivating factors (mean score > 8) included potential benefit to other women's health, improvement to one's own condition, and participation in scientific advancement. Weak motivating factors (mean score < 3) included financial compensation, making one's doctor happy, and use of 'natural' products. No difference was detected between clinical and basic science study participants.
This study is the first study to specifically investigate the factors that motivate women to take part in endometriosis research. Understanding why women choose to take part in such research is important to the integrity of the informed consent process. The factors most strongly motivating women to participate in endometriosis research related to improving personal or public health; the weakest, to financial compensation and pleasing the doctor.
本研究的目的是确定促使女性参与子宫内膜异位症研究的因素，并确定参与临床研究与基础科学研究的女性在这些因素上是否存在差异。
连续选取24名自愿参与子宫内膜异位症相关研究的女性，要求她们用自己的话说明选择成为志愿者的原因。此外，要求这些女性对16个可能的激励因素进行0至10分的评分。信息通过匿名自填问卷的形式收集。
强烈的激励因素（平均得分>8）包括对其他女性健康的潜在益处、自身状况的改善以及对科学进步的参与。较弱的激励因素（平均得分<3）包括经济补偿、让医生高兴以及使用“天然”产品。临床研究参与者和基础科学研究参与者之间未发现差异。
本研究是首次专门调查促使女性参与子宫内膜异位症研究的因素的研究。了解女性为何选择参与此类研究对于知情同意过程的完整性很重要。促使女性参与子宫内膜异位症研究的最强烈因素与改善个人或公共健康有关；最薄弱的因素是经济补偿和取悦医生。
