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将大脑中动脉动脉瘤的血管内治疗作为首选:92例动脉瘤的单中心经验

Endovascular treatment of middle cerebral artery aneurysms as first option: a single center experience of 92 aneurysms.

作者信息

Quadros R S, Gallas S, Noudel R, Rousseaux P, Pierot L

机构信息

Department of Neuroradiology, University Hospital of Reims, Reims, France.

出版信息

AJNR Am J Neuroradiol. 2007 Sep;28(8):1567-72. doi: 10.3174/ajnr.A0595.

Abstract

BACKGROUND AND PURPOSE

We conducted a retrospective evaluation of the results of endovascular treatment (EVT) of middle cerebral artery aneurysms (MCAAs) in a center where embolization is the first treatment option considered.

MATERIALS AND METHODS

Ninety-two MCAAs were diagnosed in 87 patients between September 2001 and January 2006. The strategy of treatment (endovascular versus surgical), the clinical and angiographic results of embolization, and the ensuing complications are described.

RESULTS

Initially, 59 aneurysms (64.1%) in 55 patients were embolized, 18 (19.6%) were clipped, and 15 (16.3%) were not treated. Four endovascular procedures failed (7.3%), and 55 aneurysms in 51 patients were finally treated by embolization. During the procedure, complications occurred in 13 patients (25.5%) comprising 3 ruptures and 10 thromboembolisms. In the follow-up, 4 patients having a preoperative complication had a modified Rankin scale more than 2 (3 patients [5.9%]) or died (1 patient [2.0%]). Of the 55 embolized aneurysms, according to the Raymond scale, 23 (41.8%) were completely occluded, 24 (43.6%) retained a residual neck, and 8 (14.6%) were residual at the end of the first procedure. No bleeding was detected during the follow-up period in the embolized patients.

CONCLUSION

EVT of MCAA is effective for preventing rebleeding episodes within the first year of treatment judging by historical controls. The real question is whether clipping or coiling of MCAAs is better in terms of reducing rebleeding rates and complications rates in the long term, and such a determination would require a far larger number of patients over a much longer observation period.

摘要

背景与目的

我们在一个将栓塞作为首选治疗方案的中心,对大脑中动脉动脉瘤(MCAAs)的血管内治疗(EVT)结果进行了回顾性评估。

材料与方法

2001年9月至2006年1月期间,87例患者被诊断出92个MCAAs。描述了治疗策略(血管内治疗与手术治疗)、栓塞的临床和血管造影结果以及随后的并发症。

结果

最初,55例患者中的59个动脉瘤(64.1%)接受了栓塞治疗,18个(19.6%)进行了夹闭手术,15个(16.3%)未接受治疗。4例血管内治疗失败(7.3%),51例患者中的55个动脉瘤最终接受了栓塞治疗。在治疗过程中,13例患者(25.5%)出现并发症,包括3例破裂和10例血栓栓塞。在随访中,4例术前有并发症的患者改良Rankin量表评分超过2分(3例患者[5.9%])或死亡(1例患者[2.0%])。根据Raymond量表,55个栓塞的动脉瘤中,23个(41.8%)完全闭塞,24个(43.6%)残留颈部,8个(14.6%)在首次治疗结束时仍有残留。在栓塞患者的随访期间未检测到出血。

结论

根据历史对照判断,MCAAs的EVT在治疗的第一年对预防再出血有效。真正的问题是,就长期降低再出血率和并发症率而言,MCAAs的夹闭或栓塞哪种更好,而这需要在更长的观察期内纳入大量患者才能确定。

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