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隐形眼镜相关微生物性角膜炎中隐形眼镜培养物与角膜刮片之间的关联

Association between cultures of contact lens and corneal scraping in contact lens related microbial keratitis.

作者信息

Das Sujata, Sheorey Harsha, Taylor Hugh R, Vajpayee Rasik B

机构信息

Centre for Eye Research Australia, University of Melbourne, Melbourne, Australia.

出版信息

Arch Ophthalmol. 2007 Sep;125(9):1182-5. doi: 10.1001/archopht.125.9.1182.

Abstract

OBJECTIVE

To study the association between cultures of contact lens and corneal scraping in contact lens-related microbial keratitis.

METHODS

A retrospective analysis of the culture results of corneal scrapings and contact lenses of patients with contact lens-related microbial keratitis who were initially seen at Royal Victorian Eye and Ear Hospital, Melbourne, Australia, between January 1, 2001, and December 31, 2004, was conducted.

RESULTS

Fifty eye specimens of 49 patients were included in the study. Corneal scrapings and contact lenses were culture positive in 17 eyes (34%) and in 35 eyes (70%), respectively. In 13 eyes, corneal scrapings and contact lenses yielded identical organisms. Serratia marcescens was the most common organism isolated from the corneal scrapings and from the contact lenses.

CONCLUSION

Contact lens culture may sometimes give a clue to the organism involved in cases of microbial keratitis in which the corneal scraping is culture negative and may help in choosing the appropriate antimicrobial therapy.

摘要

目的

研究隐形眼镜培养物与隐形眼镜相关性微生物性角膜炎患者角膜刮片之间的关联。

方法

对2001年1月1日至2004年12月31日期间在澳大利亚墨尔本皇家维多利亚眼耳医院初诊的隐形眼镜相关性微生物性角膜炎患者的角膜刮片和隐形眼镜培养结果进行回顾性分析。

结果

49例患者的50只眼标本纳入研究。角膜刮片和隐形眼镜培养阳性分别为17只眼(34%)和35只眼(70%)。13只眼中,角膜刮片和隐形眼镜培养出相同的微生物。粘质沙雷菌是从角膜刮片和隐形眼镜中分离出的最常见微生物。

结论

在角膜刮片培养阴性的微生物性角膜炎病例中,隐形眼镜培养有时可能为所涉及的微生物提供线索,并有助于选择合适的抗菌治疗。

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