Joseph K S, Liston Robert M, Dodds Linda, Dahlgren Leanne, Allen Alexander C
Perinatal Epidemiology Research Unit, Department of Obstetrics and Gynaecology, Dalhousie University and the IWK Health Centre, Halifax, NS.
CMAJ. 2007 Sep 11;177(6):583-90. doi: 10.1503/cmaj.061198.
The health care system in Canada provides essential health services to all women irrespective of socioeconomic status. Our objective was to determine whether perinatal and infant outcomes varied by family income and other socioeconomic factors in this setting.
We included all 92,914 women who delivered in Nova Scotia between 1988 and 1995 following a singleton pregnancy. Family income was obtained for 76,440 of these women through a confidential link to income tax records and was divided into 5 groups. Outcomes studied included pregnancy complications, preterm birth, small-for-gestational-age live birth, perinatal death, serious neonatal morbidity, postneonatal death and infant death. Logistic regression models were used to adjust for potential confounders.
Compared with women in the highest family income group, those in the lowest income group had significantly higher rates of gestational diabetes (crude rate ratio [RR] 1.44, 95% confidence interval [CI] 1.21-1.73), preterm birth (crude RR 1.20, 95% CI 1.06-1.35), small-for-gestational-age live birth (crude RR 1.81, 95% CI 1.66-1.97) and postneonatal death (crude RR 5.54, 95% CI 2.21-13.9). The opposite was true for rates of perinatal death (crude RR 0.74, 95% CI 0.56-0.96), and there was no significant difference between the 2 groups in the composite of perinatal death or serious neonatal morbidity (crude RR 1.01, 95% CI 0.82-1.24). Adjustment for behavioural and lifestyle factors accentuated or attenuated socioeconomic differences.
Lower family income is associated with increased rates of gestational diabetes, small-for-gestational-age live birth and postneonatal death despite health care services being widely available at no out-of-pocket expense.
加拿大的医疗保健系统为所有女性提供基本医疗服务,不论其社会经济地位如何。我们的目的是确定在这种情况下围产期和婴儿结局是否因家庭收入及其他社会经济因素而有所不同。
我们纳入了1988年至1995年间在新斯科舍省单胎妊娠分娩的所有92,914名女性。通过与所得税记录的保密链接获取了其中76,440名女性的家庭收入,并将其分为5组。研究的结局包括妊娠并发症、早产、小于胎龄活产、围产期死亡、严重新生儿发病率、新生儿后期死亡和婴儿死亡。使用逻辑回归模型对潜在混杂因素进行调整。
与家庭收入最高组的女性相比,收入最低组的女性患妊娠期糖尿病的比例显著更高(粗率比[RR]1.44,95%置信区间[CI]1.21 - 1.73)、早产(粗RR 1.20,95% CI 1.06 - 1.35)、小于胎龄活产(粗RR 本1.81,95% CI 1.66 - 1.97)和新生儿后期死亡(粗RR 5.54,95% CI 2.21 - 13.9)。围产期死亡比例则相反(粗RR 0.74,95% CI 0.56 - 0.96),两组在围产期死亡或严重新生儿发病率的综合情况方面无显著差异(粗RR 1.01,95% CI 0.82 - 1.24)。对行为和生活方式因素进行调整后,社会经济差异有所加剧或减弱。
尽管医疗保健服务广泛提供且无需自付费用,但较低的家庭收入与妊娠期糖尿病、小于胎龄活产和新生儿后期死亡比例的增加相关。