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孕产妇肥胖和糖尿病作为不良妊娠结局的风险因素:4个种族/族裔群体之间的差异

Maternal obesity and diabetes as risk factors for adverse pregnancy outcomes: differences among 4 racial/ethnic groups.

作者信息

Rosenberg Terry J, Garbers Samantha, Lipkind Heather, Chiasson Mary Ann

机构信息

MHRA, 40 Worth St, Suite 720, New York, NY 10013, USA.

出版信息

Am J Public Health. 2005 Sep;95(9):1545-51. doi: 10.2105/AJPH.2005.065680.

Abstract

OBJECTIVES

We examined associations between obesity, diabetes, and 3 adverse pregnancy outcomes--primary cesarean delivery, preterm birth, and low birth-weight (LBW)--by racial/ethnic group. Our goal was to better understand how these associations differentially impact birth outcomes by group in order to develop more focused interventions.

METHODS

Data were collected from the 1999, 2000, and 2001 New York City birth files for 329,988 singleton births containing information on prepregnancy weight and prenatal weight gain. Separate logistic regressions for 4 racial/ethnic groups predicted the adverse pregnancy outcomes associated with diabetes. Other variables in the regressions included obesity, excess weight gain, hypertension, preeclampsia, and substance use during pregnancy (e.g., smoking).

RESULTS

Chronic and gestational diabetes were significant risks for a primary cesarean and for preterm birth in all women. Diabetes as a risk for LBW varied by group. For example, whereas chronic diabetes increased the risk for LBW among Asians, Hispanics, and Whites (adjusted odds ratios=2.28, 1.69, and 1.59), respectively, it was not a significant predictor of LBW among Blacks.

CONCLUSIONS

In this large, population-based study, obesity and diabetes were independently associated with adverse pregnancy outcomes, highlighting the need for women to undergo lifestyle changes to help them control their weight during the childbearing years and beyond.

摘要

目的

我们按种族/族裔群体研究了肥胖、糖尿病与三种不良妊娠结局——初次剖宫产、早产和低出生体重(LBW)之间的关联。我们的目标是更好地了解这些关联如何因群体不同而对出生结局产生差异影响,以便制定更有针对性的干预措施。

方法

从1999年、2000年和2001年纽约市出生档案中收集了329,988例单胎分娩的数据,这些数据包含孕前体重和孕期体重增加的信息。对4个种族/族裔群体分别进行逻辑回归,预测与糖尿病相关的不良妊娠结局。回归中的其他变量包括肥胖、体重增加过多、高血压、先兆子痫和孕期物质使用情况(如吸烟)。

结果

慢性糖尿病和妊娠期糖尿病对所有女性来说都是初次剖宫产和早产的显著风险因素。糖尿病作为低出生体重的风险因素因群体而异。例如,慢性糖尿病分别增加了亚洲人、西班牙裔和白人低出生体重的风险(调整后的优势比分别为2.28、1.69和1.59),但在黑人中它不是低出生体重的显著预测因素。

结论

在这项基于人群的大型研究中,肥胖和糖尿病与不良妊娠结局独立相关,这突出表明女性需要改变生活方式,以帮助她们在育龄期及之后控制体重。

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