Weigelt John A
Department of Surgery, Division of Trauma/Critical Care, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Cleve Clin J Med. 2007 Aug;74 Suppl 4:S29-37. doi: 10.3949/ccjm.74.suppl_4.s29.
Complicated intra-abdominal infections remain a major challenge for surgeons and internists because of their association with high morbidity and mortality. For optimal outcome, these infections require a combination of appropriate and timely surgical source control and adjunctive broad-spectrum antimicrobial therapy. This review discusses criteria for choosing empiric antimicrobial therapy, outlines available treatment options, and highlights new antimicrobial therapies for these infections.
复杂性腹腔内感染因其与高发病率和死亡率相关，仍然是外科医生和内科医生面临的重大挑战。为了获得最佳治疗效果，这些感染需要适当且及时的手术源头控制与辅助性广谱抗菌治疗相结合。本综述讨论了选择经验性抗菌治疗的标准，概述了可用的治疗方案，并强调了针对这些感染的新型抗菌治疗方法。
