Bilewicz R, Wierzchowska M, Burduk P K, Szukalski J
Katedra i Klinika Otolaryngologii, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy, Uniwersytetu Mikolaja Kopernika w Toruniu.
Otolaryngol Pol. 2007;61(3):325-8. doi: 10.1016/S0030-6657(07)70436-5.
Malignant fibrohistiocytoma is one of the rare neoplasms of the larynx. It has nonepithelial origin. The most common sites of the neoplasm are: limbs, trunk and retroperitoneal space. Other localizations within head and neck are very rare. There are 5 histologic types. The most common is pleomorphic type. It is built of histiocytes, fibroblasts and multinuclear giant cells. An examination of the neoplasms consists of microscopic and immunohistologic examination with identification specific tissue markers and intermediate filaments of proteins. Treatment methods of the neoplasms are radical surgery, radiotherapy, chemiotherapy and associate methods of therapy. Prognosis is very bad.
[corrected] We present 71 years old man with croak for four mounths. The tumor of the larynx was examined in laryngoscopy. Biopsy of the tumor confirmed malignant fibrohistiocytoma. Laser surgery (chordectomy) was used to treatment this tumor without radiotherapy.
One year observation of the patient didn't show recurrence of neoplasm, but he had only croak.
Malignant fibrohistiocytoma of the larynx doesn't differ from other malignant neoplasms of the larynx. Malignant fibrohistiocytoma of the larynx is very rare malignant neoplasms of the larynx.
恶性纤维组织细胞瘤是喉部罕见的肿瘤之一。它起源于非上皮组织。该肿瘤最常见的部位是四肢、躯干和腹膜后间隙。头颈部的其他部位则非常罕见。它有5种组织学类型。最常见的是多形性类型。它由组织细胞、成纤维细胞和多核巨细胞组成。对肿瘤的检查包括显微镜检查和免疫组织学检查，以识别特定的组织标志物和蛋白质中间丝。肿瘤的治疗方法包括根治性手术、放疗、化疗及联合治疗方法。预后非常差。
[已修正] 我们报告一名71岁男性，声音嘶哑4个月。在喉镜检查中对喉部肿瘤进行了检查。肿瘤活检确诊为恶性纤维组织细胞瘤。采用激光手术（声带切除术）治疗该肿瘤，未进行放疗。
对患者进行一年的观察，未发现肿瘤复发，但他仍有声音嘶哑。
喉部恶性纤维组织细胞瘤与喉部其他恶性肿瘤并无差异。喉部恶性纤维组织细胞瘤是喉部非常罕见的恶性肿瘤。
