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对于开胸术后的疼痛缓解,肋间导管镇痛比肋间神经阻滞更有效。

Intercostal catheter analgesia is more efficient vs. intercostal nerve blockade for post-thoracotomy pain relief.

作者信息

Kristek Jozo, Kvolik Slavica, Sakić Kata, Has Borislav, Prlić Lidija

机构信息

Department of Thoracic Surgery, University Hospital "Osijek", Osijek, Croatia.

出版信息

Coll Antropol. 2007 Jun;31(2):561-6.

Abstract

A pain after thoracotomy may result in a postoperative hypoventilation and lead to atelectases and pneumonia. This study was aimed to compare two analgesic regimens after posterolateral thoracotomy. 80 patients (40-70 years) undergoing thoracotomy were randomized to intercostal catheter analgesia (group A, n = 40) and intercostal nerve block (group B, n = 40). Patients in group A were given 20 mL of 0.5% bupivacaine injections twice a day by intercostal catheter. Intercostal nerve blockade was performed using 5 mL of 0.5% bupivacaine. Intercostal nerve in thoracotomy wound, nerves below and above thoracotomy wound was also injected. PaO2, PaCO2, FVC, FEV1 and visual analog pain scale (VAS) were obtained preoperatively, 24, 48 and 72 hours after operation. Postoperative complications were recorded at the patient discharge. Differences between groups were calculated using Mann-Whitney, KW test and chi square test. The arterial blood gas analyses did not show statistically significant change in any group and time according to the baseline values. FVC and FEV1 decreased significantly in both groups at first postoperative day according to baseline measurements. Patients in B group had significantly higher FEV1 values in the third postoperative day (73.05 +/- 11.25 in A vs. 83.50 +/- 9.17 in B group, p < 0.05). Intercostal catheter analgesia resulted in significantly lower postoperative VAS scores and reduced opioid requirement as compared to intercostal nerve blockade. No differences in the postoperative complications were observed between groups.

摘要

开胸术后疼痛可能导致术后通气不足,并引发肺不张和肺炎。本研究旨在比较后外侧开胸术后两种镇痛方案。80例(40 - 70岁)接受开胸手术的患者被随机分为肋间导管镇痛组(A组,n = 40)和肋间神经阻滞组(B组,n = 40)。A组患者通过肋间导管每天两次给予20 mL 0.5%布比卡因注射液。使用5 mL 0.5%布比卡因进行肋间神经阻滞。开胸伤口处、开胸伤口上下的肋间神经也进行注射。在术前、术后24、48和72小时获取动脉血氧分压(PaO2)、动脉血二氧化碳分压(PaCO2)、用力肺活量(FVC)、第一秒用力呼气量(FEV1)和视觉模拟疼痛评分(VAS)。在患者出院时记录术后并发症。使用曼 - 惠特尼检验、KW检验和卡方检验计算组间差异。根据基线值,动脉血气分析在任何组和时间均未显示出统计学上的显著变化。与基线测量值相比,两组在术后第一天FVC和FEV1均显著下降。B组患者在术后第三天的FEV1值显著更高(A组为73.05±11.25,B组为83.50±9.17,p < 0.05)。与肋间神经阻滞相比,肋间导管镇痛导致术后VAS评分显著更低,且阿片类药物需求量减少。两组术后并发症无差异。

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