Razani Jill, Casas Rachel, Wong Jennifer T, Lu Po, Alessi Cathy, Josephson Karen
Department of Psychology, California State University, Northridge, California 91330-8255, USA.
Appl Neuropsychol. 2007;14(3):208-14. doi: 10.1080/09084280701509125.
There is very little research regarding the relationship between tests of executive functioning and actual functional ability in patients with dementia. Thirty-three patients diagnosed with dementia and 35 age- and education-matched healthy controls were administered tests of executing functioning and an observation- and informant-based activities of daily living (ADL). As expected, the results revealed that the controls outperformed the dementia patients on the executive and ADL tests. Additionally, executive functioning correlated significantly with aspects of functional ability in patients with dementia. This relationship was strongest for tests of verbal fluency and a complex test of cognitive flexibility and reasoning ability (i.e., Wisconsin Card Sorting Test). These findings suggest that some executive function tests are more sensitive than others for predicting specific functional abilities and that they may be most useful to healthcare professionals for treatment planning.
关于痴呆症患者执行功能测试与实际功能能力之间的关系，相关研究非常少。对33名被诊断为痴呆症的患者以及35名年龄和教育程度相匹配的健康对照者进行了执行功能测试以及基于观察和 informant 的日常生活活动（ADL）测试。正如预期的那样，结果显示，在执行功能和ADL测试中，对照组的表现优于痴呆症患者。此外，执行功能与痴呆症患者的功能能力方面显著相关。对于言语流畅性测试以及认知灵活性和推理能力的复杂测试（即威斯康星卡片分类测试），这种关系最为强烈。这些发现表明，一些执行功能测试在预测特定功能能力方面比其他测试更敏感，并且它们可能对医疗保健专业人员进行治疗规划最为有用。
