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丝裂霉素C局部应用治疗食管及气管支气管狭窄:2例报告

Topical application of mitomycin C in the treatment of esophageal and tracheobronchial stricture: a report of 2 cases.

作者信息

Daher Paul, Riachy Edward, Georges Beyrouthy, Georges Dabar, Adib Moukarzel

机构信息

Department of Pediatric Surgery, Hotel Dieu de France Hospital, Beirut, Lebanon.

出版信息

J Pediatr Surg. 2007 Sep;42(9):E9-11. doi: 10.1016/j.jpedsurg.2007.06.007.

DOI:10.1016/j.jpedsurg.2007.06.007
PMID:17848232
Abstract

We present 2 cases of successful treatment of recurrent anastomotic strictures using a topical application of mitomycin C. In the first case, a 4-year-old boy had a cervical cyst excised, which appeared to be an ectopic gastric mucosa. He consequently presented severe stenosis at the origin of the cervical esophagus that needed repeated balloon dilatations. The second case is about a 12-year-old girl who presented a traumatic complete rupture of the right mainstem bronchus managed by primary repair, with subsequent anastomotic stricture. Both patients were successfully managed with topical application of mitomycin C (1 mg/mL), and needed no more dilatations.

摘要

我们报告了2例使用丝裂霉素C局部应用成功治疗复发性吻合口狭窄的病例。第一例,一名4岁男孩切除了一个颈部囊肿,该囊肿似乎是异位胃黏膜。随后,他在颈段食管起始处出现严重狭窄,需要反复进行球囊扩张。第二例是一名12岁女孩,她因右主支气管创伤性完全破裂接受了一期修复,随后出现吻合口狭窄。两名患者均通过局部应用丝裂霉素C(1mg/mL)成功治疗,无需再进行扩张。

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