Intenzo Charles M, Jabbour Serge, Lin Henry C, Miller Jeffrey L, Kim Sung M, Capuzzi David M, Mitchell Edith P
Department of Radiology, Thomas Jefferson University School of Medicine, Philadelphia, PA 19107, USA.
Radiographics. 2007 Sep-Oct;27(5):1355-69. doi: 10.1148/rg.275065729.
Radionuclide imaging is often used in the diagnosis and work-up of a wide range of neoplasms, on the basis of the biologic behavior of the tumor. Neuroendocrine tumors are a subgroup of neoplasms that are generally small and slow growing, and consequently their identification with conventional anatomic imaging can be difficult. Depending on the physiologic properties of the tumor, functional images obtained with radionuclides are often complementary to anatomic images, not only in the localization of the tumor and its metastases, but also in the assessment of prognosis and response to therapy. Familiarity with the choice of the appropriate radiopharmaceutical, proper imaging protocols, and the wide range of imaging patterns will enable the radiologist to guide the clinician in case management.
基于肿瘤的生物学行为,放射性核素成像常用于多种肿瘤的诊断和检查。神经内分泌肿瘤是肿瘤的一个亚组,通常体积较小且生长缓慢,因此通过传统解剖成像来识别它们可能会很困难。根据肿瘤的生理特性,用放射性核素获得的功能图像通常可补充解剖图像,不仅在肿瘤及其转移灶的定位方面,而且在预后评估和治疗反应评估方面。熟悉合适放射性药物的选择、恰当的成像方案以及广泛的成像模式,将使放射科医生能够在病例管理中指导临床医生。