Enjolras O
Service de dermatologie, hôpital Tarnier (CHU Cochin), Paris.
Rev Prat. 1991 Oct 15;41(22):2174-6.
Most of psoriatic patients require topical therapy. Dermal application of drugs may be the unique treatment; but it can also combined with oral drugs, or phototherapy. Patients are treated at home or in day-care centers; some require hospitalization. Topical corticosteroids are widely used: abuses are frequently observed, therefore skin and systemic side-effects may occur to varying degrees. Tars are still useful. Short-contact anthralin is active and well tolerated, and compliance is better than with conventional tar therapy, especially in children. Topical mechlorethamine clears the plaques but contact dermatitis may occur. New therapeutic approaches include Vitamin D3 analogues.
大多数银屑病患者需要局部治疗。药物经皮应用可能是唯一的治疗方法；但也可与口服药物或光疗联合使用。患者在家中或日间护理中心接受治疗；一些患者需要住院治疗。局部用皮质类固醇广泛使用：经常观察到滥用情况，因此可能会出现不同程度的皮肤和全身副作用。焦油制剂仍然有用。短接触蒽林有效且耐受性良好，依从性优于传统焦油疗法，尤其是在儿童中。局部用氮芥可清除斑块，但可能会发生接触性皮炎。新的治疗方法包括维生素D3类似物。
