Alhyraba M, Grim S A, Benedetti E, Clark N M
Department of Internal Medicine, Section of Infectious Diseases, University of Illinois at Chicago, Chicago, Illinois 60612, USA.
Transpl Infect Dis. 2007 Dec;9(4):343-6. doi: 10.1111/j.1399-3062.2007.00276.x.
Cytomegalovirus (CMV) is a cause of significant morbidity and mortality in solid organ transplant recipients. Gastrointestinal (GI) tract infection by CMV in this population can cause symptomatic disease, which typically manifests as fever, abdominal pain, nausea, and bloody diarrhea. Erosive lesions of the GI mucosa are often evident on endoscopic exam. We report an unusual presentation of CMV enteritis in a kidney and liver transplant recipient with the development of acute onset voluminous watery diarrhea in the absence of other typical symptoms and subsequent progression to hypovolemic shock and acute renal failure. This case emphasizes the atypical presentations of common opportunistic infections that may occur in immunosuppressed hosts.
巨细胞病毒（CMV）是实体器官移植受者发病和死亡的重要原因。该人群中CMV引起的胃肠道（GI）感染可导致症状性疾病，通常表现为发热、腹痛、恶心和血性腹泻。内镜检查时胃肠道黏膜的糜烂性病变常很明显。我们报告了1例肾肝移植受者CMV肠炎的不寻常表现，该患者急性起病，出现大量水样腹泻，无其他典型症状，随后进展为低血容量性休克和急性肾衰竭。该病例强调了免疫抑制宿主中常见机会性感染可能出现的非典型表现。
