Martínez-Aguayo Alejandro, Araneda Juan Carlos, Fernandez Daniela, Gleisner Andrea, Perez Virginia, Codner Ethel
Institute of Maternal and Child Research, School of Medicine, University of Chile, Santiago, Chile.
Pediatr Diabetes. 2007 Oct;8(5):265-71. doi: 10.1111/j.1399-5448.2007.00307.x.
Substance abuse in adolescents with diabetes mellitus (DM) is associated with the development of acute and chronic complications.
To determine the prevalence of alcohol, tobacco, and illicit drug consumption in adolescents with DM and compare it with the prevalence in a large contemporary control (C) group.
Adolescents with and without DM, who were attending 8th-12th grades, answered a structured written questionnaire, which evaluates the voluntary declaration of tobacco, alcohol, and illicit drug consumption. Subjects with DM were recruited from free diabetes camps or public hospitals (n = 193). The C group was obtained from a nationwide study of prevalence of substance abuse (n = 58,489). For illicit drugs (marijuana, cocaine, or cocaine sulfate), results are shown as life prevalence (ever used the substance). For alcohol and tobacco, results are shown as last month prevalence (the substance was used during the last month).
Adolescents with DM showed a lower last month prevalence of tobacco and alcohol consumption than C (27.7 vs. 39.0%, p < 0.01 and 30.1 vs. 39.2%, p < 0.01, respectively). DM group had a lower life prevalence rate of illicit drugs than C group (9.6 vs. 22.2%, respectively; p < 0.01). A lower prevalence of tobacco, alcohol, and illicit drug use in DM group compared with C group was observed in grades 8, 9, and 10. However, a similar frequency of consumption was observed in 11th and 12th grades.
Compared with healthy youth, DM patients use less tobacco, alcohol, and illicit drugs during the first years of adolescence but not later.
糖尿病(DM)青少年的药物滥用与急慢性并发症的发生有关。
确定DM青少年中酒精、烟草和非法药物消费的患病率,并与大型当代对照组(C组)的患病率进行比较。
就读于8至12年级的有或无DM的青少年回答了一份结构化书面问卷,该问卷评估了烟草、酒精和非法药物消费的自愿申报情况。DM患者从免费糖尿病营地或公立医院招募(n = 193)。C组来自一项全国性药物滥用患病率研究(n = 58,489)。对于非法药物(大麻、可卡因或硫酸可卡因),结果以终生患病率(曾使用过该物质)表示。对于酒精和烟草,结果以上月患病率(上月使用过该物质)表示。
DM青少年的上月烟草和酒精消费患病率低于C组(分别为27.7%对39.0%,p < 0.01;30.1%对39.2%,p < 0.01)。DM组的非法药物终生患病率低于C组(分别为9.6%对22.2%;p < 0.01)。在8、9和10年级中,观察到DM组的烟草、酒精和非法药物使用患病率低于C组。然而,在11和12年级中观察到类似的消费频率。
与健康青少年相比,DM患者在青春期的头几年使用烟草、酒精和非法药物较少,但后期并非如此。