Stimulation of microsomal drug-metabolizing enzymes in rat liver by 1,1,1,-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT), pregnenolone-16 alpha-carbonitrile (PCN), and polychlorinated biphenyls (PCB's).
作者信息
Vainio H
出版信息
Environ Qual Saf Suppl. 1975;3:386-90.
PMID:178505
Abstract
摘要
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1
Stimulation of microsomal drug-metabolizing enzymes in rat liver by 1,1,1,-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT), pregnenolone-16 alpha-carbonitrile (PCN), and polychlorinated biphenyls (PCB's).1,1,1-三氯-2,2-双（对氯苯基）乙烷（滴滴涕）、孕烯醇酮-16α-腈（PCN）和多氯联苯（PCBs）对大鼠肝脏微粒体药物代谢酶的刺激作用。
Environ Qual Saf Suppl. 1975;3:386-90.
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Long-term effects of single and combined doses of DDT and PCB on drug-metabolizing enzymes in rat liver.滴滴涕（DDT）和多氯联苯（PCB）单剂量及联合剂量对大鼠肝脏药物代谢酶的长期影响。
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Enhancement of hepatic microsomal drug oxidation and glucuronidation in rat by 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT).1,1,1-三氯-2,2-双（对氯苯基）乙烷（滴滴涕）对大鼠肝脏微粒体药物氧化和葡萄糖醛酸化的增强作用。
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Age- and sex-dependent induction of liver microsomal benzo[a]pyrene hydroxylase activity in rats treated with pregnenolone-16 alpha-carbonitrile (PCN).孕烯醇酮-16α-腈（PCN）处理的大鼠中肝微粒体苯并[a]芘羟化酶活性的年龄和性别依赖性诱导。
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Studies on the pregnenolone-16 alpha-carbonitrile-inducible form of rat liver microsomal cytochrome P-450 and UDP-glucuronosyltransferase.孕烯醇酮-16α-腈诱导型大鼠肝微粒体细胞色素P-450和尿苷二磷酸葡萄糖醛酸转移酶的研究
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Reduction of thyroid hormone levels and alteration of thyroid function by four representative UDP-glucuronosyltransferase inducers in rats.四种代表性尿苷二磷酸葡萄糖醛酸基转移酶诱导剂对大鼠甲状腺激素水平的降低及甲状腺功能的改变
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UDP glucuronosyltransferase and mixed function oxidase activity in microsomes prepared by differential centrifugation and calcium aggregation.通过差速离心和钙聚集制备的微粒体中的UDP葡萄糖醛酸基转移酶和混合功能氧化酶活性。
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