Punda-Polić V, Luksić B, Capkun V
Department of Clinical Microbiology, Split University Medical School and Split University Hospital, Split, Croatia.
Epidemiol Infect. 2008 Jul;136(7):972-9. doi: 10.1017/S0950268807009491. Epub 2007 Sep 13.
We determined the epidemiological features of three zoonoses in hospitalized patients in southern Croatia. Patients were diagnosed by serological testing. Clinical and epidemiological data were also collected. Between 1982 and 2002, Mediterranean spotted fever (MSF) was diagnosed in 126 (incidence rate 1.27/100,000 per year), murine typhus (MT), in 57 (incidence rate 0.57/100,000 per year), and Q fever in 170 (incidence rate 1.7/100,000 per year) patients. MSF and Q fever were characterized by a marked seasonality. Incidences of Q fever and of MSF were higher for males than for females (P<0.0001 and P=0.0024, respectively). The most frequent of the three zoonoses in children was MSF. Q fever and MT cases were mostly seen in the 21-50 years age group. We found no statistically significant differences between season- and gender-specific incidence rates of MT. Whereas infections due to rickettsiae decreased, the incidence of Q fever increased over the last 12 years of the study.
我们确定了克罗地亚南部住院患者中三种人畜共患病的流行病学特征。患者通过血清学检测进行诊断。同时收集了临床和流行病学数据。1982年至2002年间，126例患者被诊断为地中海斑疹热（MSF）（发病率为每年1.27/10万），57例患者被诊断为鼠型斑疹伤寒（MT）（发病率为每年0.57/10万），170例患者被诊断为Q热（发病率为每年1.7/10万）。MSF和Q热具有明显的季节性特征。Q热和MSF的发病率男性高于女性（分别为P<0.0001和P=0.0024）。三种人畜共患病在儿童中最常见的是MSF。Q热和MT病例大多出现在21至50岁年龄组。我们发现MT的季节和性别特异性发病率之间没有统计学上的显著差异。在研究的最后12年里，立克次体感染减少，而Q热的发病率增加。
