Mintz L J, Sarwark J F, Dias L S, Schafer M F
University of Iowa Hospitals and Clinics, Iowa City.
Spine (Phila Pa 1976). 1991 Aug;16(8 Suppl):S348-50.
The progression of congenital lumbar kyphosis in myelomeningocele is a well-known problem, but rates of progression are not well documented in the literature. Fifty-one children with congenital kyphosis and myelomeningocele were followed for an average of 4.8 years. Minimum follow-up was 1 year. Group I (35 patients) had initial radiographs at 1 year of age or less. Group II (16 patients) had radiographs taken after the age of 1 year. Curves less than or equal to 90 degrees in Group I progressed 7.7 degrees/yr; those greater than 90 degrees progressed 12.1 degrees/yr. Curves less than or equal to 90 degrees and greater than 90 degrees progressed at similar rates, regardless of initial curve magnitude: 6.4 degrees/yr and 6.7 degrees/yr, respectively. No correlation existed among the rate of curve progression, the frequency of shunt revisions, or the presence of vertebral anomalies, aside from the dysraphism.
先天性脊柱裂并发先天性腰椎后凸的进展是一个众所周知的问题，但文献中关于其进展速率的记录并不完善。对51例患有先天性脊柱后凸和脊柱裂的儿童进行了平均4.8年的随访。最短随访时间为1年。第一组（35例患者）在1岁及1岁以下时进行了初始X线片检查。第二组（16例患者）在1岁以后进行了X线片检查。第一组中小于或等于90度的曲线每年进展7.7度；大于90度的曲线每年进展12.1度。小于或等于90度以及大于90度的曲线进展速率相似，与初始曲线大小无关：分别为每年6.4度和6.7度。除脊柱裂外，曲线进展速率、分流修正频率或椎体异常的存在之间均无相关性。
