Torrey E Fuller
Laboratory Research, The Stanley Medical Research Institute, 8401 Connecticut Avenue, Suite 200, Chevy Chase, MD 20815, USA.
Schizophr Res. 2007 Dec;97(1-3):215-25. doi: 10.1016/j.schres.2007.08.023. Epub 2007 Sep 12.
Studies of the neuroanatomical localization of schizophrenia have not given sufficient attention to the inferior parietal lobule (IPL).
A search of the medical literature was carried out for links between schizophrenia and the IPL.
Structural differences in the IPL in schizophrenia were reported by 10 recent neuroimaging studies, although the studies did not all agree with each other. Functional differences in the IPL in schizophrenia have been prominently reported in four areas: sensory integration, body image, concept of self, and executive function.
The IPL appears to be an important, but relatively neglected, component of the frontal-limbic-temporal-parietal neural network involved in the schizophrenia disease process. To encourage histopathological research of this area, the Stanley Medical Research Institute is making available a new collection of sucrose-fixed IPL tissue from 25 individuals with schizophrenia and 25 matched controls. Additional imaging and functional studies are needed to better define the network and role of the IPL.
对精神分裂症神经解剖定位的研究尚未充分关注顶下小叶（IPL）。
检索医学文献以寻找精神分裂症与IPL之间的联系。
最近10项神经影像学研究报告了精神分裂症患者IPL的结构差异，尽管这些研究并非完全一致。精神分裂症患者IPL的功能差异主要在四个方面被报道：感觉整合、身体意象、自我概念和执行功能。
IPL似乎是参与精神分裂症疾病过程的额-边缘-颞-顶神经网络的一个重要但相对被忽视的组成部分。为鼓励对该区域进行组织病理学研究，斯坦利医学研究所提供了一个新的蔗糖固定的IPL组织样本集，来自25名精神分裂症患者和25名匹配的对照。还需要更多的影像学和功能研究来更好地界定IPL的神经网络和作用。
