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Telomeres.

作者信息

Blackburn E H

机构信息

Department of Microbiology and Immunology, University of California, San Francisco 94143.

出版信息

Trends Biochem Sci. 1991 Oct;16(10):378-81. doi: 10.1016/0968-0004(91)90155-o.

DOI:10.1016/0968-0004(91)90155-o
PMID:1785140
Abstract

Telomeres are specialized structures at the ends of eukaryotic linear chromosomes, consisting of protein-bound tandemly repeated simple DNA sequences. Telomeric DNA is unique in that it is copied from an RNA template that forms part of the enzyme, telomerase. This review discusses the synthesis and maintenance of these unusual structures.

摘要

相似文献

1
Telomeres.
Trends Biochem Sci. 1991 Oct;16(10):378-81. doi: 10.1016/0968-0004(91)90155-o.
2
The ends and the middle: putting chromosomes together.
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3
Telomeres, telomerase and senescence.端粒、端粒酶与衰老
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4
Telomerase is an unusual RNA-containing enzyme. A review.端粒酶是一种不同寻常的含RNA酶。一篇综述。
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5
Developmentally programmed healing of chromosomes by telomerase in Tetrahymena.端粒酶在四膜虫中对染色体进行发育编程修复。
Cell. 1991 Nov 15;67(4):823-32. doi: 10.1016/0092-8674(91)90077-c.
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TLC1: template RNA component of Saccharomyces cerevisiae telomerase.TLC1：酿酒酵母端粒酶的模板RNA组分。
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Telomeres: beginning to understand the end.端粒：开始了解生命的终结
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8
Structure and function of telomeres.端粒的结构与功能。
Nature. 1991 Apr 18;350(6319):569-73. doi: 10.1038/350569a0.
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Protection against chromosome degradation at the telomeres.端粒处染色体降解的防护作用。
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