孕11至13⁺⁶周时通过超声进行胎儿性别筛查。

Fetal gender screening by ultrasound at 11 to 13(+6) weeks.

作者信息

Hsiao C H, Wang H C, Hsieh C F, Hsu J J

机构信息

Department of Obstetrics and Gynecology, Taipei City Hospital & Li Shin Hospital, Taipei City, Taiwan.

出版信息

Acta Obstet Gynecol Scand. 2008;87(1):8-13. doi: 10.1080/00016340701571905.

DOI:10.1080/00016340701571905

PMID:17851807

Abstract

BACKGROUND

To survey the accuracy of fetal gender determination during first trimester screening and scan for congenital anomalies.

METHODS

A prospective observational study was performed on 496 singleton pregnancies at the first trimester ultrasound screening. The doctor was a certified sonographer of first trimester screening by the Fetal Medicine Foundation(FMF). Ultrasound examination was performed on a GE Voluson 730 Pro, transabdominally, between 11 and 13(+6) weeks. Both transverse and mid-sagittal planes of a section of the fetal genital tubercle were performed to identify the gender. The subsequent gender at birth was obtained from karyotyping reports or hospital birth records.

RESULTS

During the study, 496 patients requested gender information at the time of first trimester screening. Of the patients it was possible to determine gender (441 out of 496), the scan achieved an overall success rate of 91.8% in correctly identifying gender. The success rate for correctly identifying fetal gender (where identification was possible) increased with gestational age, from 71.9% at 11 weeks, 92% at 12 weeks, and 98.3% at 13 weeks, respectively, where gestational age was calculated from the crown-rump length in conjunction with menstrual or ovulation dating (p<0.001). Of the 55 cases where no identification of gender was possible, 39 were in the 11-week gestational age group, representing 40.6% of this category. The overall fetal gender accuracy rate for male fetus was slightly better than female (92.5 versus 91.2%), but was not statistically significant.

CONCLUSIONS

This study demonstrated that the gestational age of the fetus has a material effect on the accuracy rate of gender determination. At 12 weeks and over, the average success rate for correctly identifying gender, where gender identification was possible, was 94.8%, with the accuracy at 13 weeks of 98.3% approaching that achieved by invasive testing. Fetal gender identification at 11

摘要

背景

调查孕早期筛查及先天性异常扫描时胎儿性别判定的准确性。

方法

对496例单胎妊娠进行孕早期超声筛查的前瞻性观察研究。医生为胎儿医学基金会（FMF）认证的孕早期筛查超声医师。使用GE Voluson 730 Pro经腹部在孕11至13（+6）周进行超声检查。对胎儿生殖结节的一段进行横切面和正中矢状面检查以确定性别。出生时的后续性别信息来自染色体核型分析报告或医院出生记录。

结果

研究期间，496例患者在孕早期筛查时要求了解胎儿性别信息。在可判定性别的患者中（496例中的441例），扫描正确识别性别的总体成功率为91.8%。正确识别胎儿性别的成功率（在可能识别的情况下）随孕周增加而升高，分别为孕11周时71.9%、孕12周时92%、孕13周时98.3%，孕周根据头臀长度结合月经或排卵日期计算（p<0.001）。在55例无法识别性别的病例中，39例在孕11周龄组，占该组的40.6%。男性胎儿的总体性别准确率略高于女性（92.5%对91.2%），但无统计学意义。