Reproductive Medicine, Department of Obstetrics and Gynaecology, Institution of Clinical Sciences, Sahlgrenska Academy,Sahlgrenska University Hospital, Go¨teborg, Sweden.
Acta Obstet Gynecol Scand. 2007 Oct;86(10):1222-30. doi: 10.1080/00016340701622393.
The objective of this study was to investigate the attitudes towards and management of single embryo transfer(SET) among Nordic in vitro fertilisation (IVF) doctors, and to present the rate of SET and multiple pregnancies in the different countries.
A questionnaire was sent to all IVF doctors in the Nordic countries (n=198, 78.5% responded). Pregnancy rates, SET and multiple births rates were extracted from registries. Main outcome measure was attitudes and management of SET.
Almost all doctors thought that a twin pregnancy compared unfavourably to a singleton. A twin rate >10% was acceptable for 5% of Swedish doctors. Corresponding figures for Finnish, Danish and Norwegian doctors were 21, 35 and 35%, respectively. For a woman <36 years, performing her first cycle and with two good quality embryos, almost all doctors would recommend SET. For a woman ≥ 36 years in a similar situation, SET would be recommended only in Sweden and Finland. The pregnancy rate per embryo transfer (ET), the SET rate 2003, the multiple birth rate, and the estimated SET rate 2004 were 33.3, 21.5, 22.7 and 25% (Denmark), 31.3, 43.4, 14 and 51%(Finland), 40.5, 10.5, 26.5 and 16% (Iceland), 30.6, 18, 25.2 and 26% (Norway), and 35.3, 55.1, 11.8 and 71% (Sweden).
The SET and multiple birth rates reflect the attitudes of Nordic IVF doctors to SET and multiple births well.When introducing SET, the attitude of the IVF doctor seems to be important.
本研究旨在调查北欧体外受精（IVF）医生对单胚胎移植（SET）的态度和管理方法，并介绍不同国家的 SET 率和多胎妊娠率。
向北欧所有 IVF 医生发送问卷（n=198，78.5% 回复）。从注册处提取妊娠率、SET 和多胎出生率数据。主要观察指标为 SET 的态度和管理。
几乎所有医生都认为双胞胎妊娠不如单胎妊娠理想。5%的瑞典医生认为双胞胎率>10%是可以接受的，而芬兰、丹麦和挪威医生的相应数字分别为 21%、35%和 35%。对于年龄<36 岁、首次接受周期治疗且有两个优质胚胎的女性，几乎所有医生都会建议进行 SET。对于年龄≥36 岁且情况相似的女性，只有在瑞典和芬兰才会建议进行 SET。2003 年的胚胎移植（ET）妊娠率、SET 率、多胎出生率和估计的 2004 年 SET 率分别为 33.3%、21.5%、22.7%和 25%（丹麦）、31.3%、43.4%、14%和 51%（芬兰）、40.5%、10.5%、26.5%和 16%（冰岛）、30.6%、18%、25.2%和 26%（挪威）和 35.3%、55.1%、11.8%和 71%（瑞典）。
SET 和多胎出生率很好地反映了北欧 IVF 医生对 SET 和多胎妊娠的态度。在引入 SET 时，IVF 医生的态度似乎很重要。
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