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食管癌和贲门癌的发病率。随时间的变化及地域差异。

Incidence of carcinoma of the oesophagus and gastric cardia. Changes over time and geographical differences.

作者信息

Falk Jens, Carstens Hanna, Lundell Lars, Albertsson Maria

机构信息

Department of Clinical Oncology, Södersjukhuset, Karolinska University Hospital, Stockholm, Sweden.

出版信息

Acta Oncol. 2007;46(8):1070-4. doi: 10.1080/02841860701403046.

Abstract

BACKGROUND

The incidence of adenocarcinoma of the oesophagus is rising in many western countries including Sweden.

METHODS

We have studied the latest data concerning this as well as trends in the incidence of squamous cell carcinoma and adenocarcinoma of gastric cardia. Data was extracted from the Swedish cancer registry and analyzed regarding gender, age, region, histology and location of tumour.

RESULTS

The results show an increasing incidence of adenocarcinoma in both oesophagus and gastric cardia. Squamous cell carcinomas show a more stable development with a slight decrease of incidence. Adenocarcinoma is now the most common histological type of cancer in the oesophageal/cardia region in Sweden. Results also suggest a possible drift in location of adenocarcinoma from gastric cardia towards oesophagus. Overall a higher incidence was found in the male population and no trends in patient age at onset could be found. Squamous cell carcinoma is still slightly more common in urban regions.

摘要

背景

在包括瑞典在内的许多西方国家,食管癌的发病率正在上升。

方法

我们研究了有关这方面的最新数据以及鳞状细胞癌和贲门腺癌的发病率趋势。数据从瑞典癌症登记处提取,并就性别、年龄、地区、组织学和肿瘤位置进行了分析。

结果

结果显示食管癌和贲门腺癌的发病率均在上升。鳞状细胞癌呈现出更稳定的发展态势,发病率略有下降。腺癌现在是瑞典食管/贲门区域最常见的癌症组织学类型。结果还表明腺癌的发病位置可能从贲门向食管转移。总体而言,男性人群的发病率更高,且未发现发病患者年龄的趋势。鳞状细胞癌在城市地区仍然略为常见。

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