Bonfils Pierre, Malinvaud David
Department of ENT-Head and Neck Surgery, European Hospital Georges Pompidou Faculty of Medicine, University Paris-Descartes, Paris, France.
Acta Otolaryngol. 2008 Feb;128(2):186-92. doi: 10.1080/00016480701387165.
Allergy does not modify the symptoms and steroid consumption (oral and local) of nasal polyposis (NP) patients after functional endoscopic sinus surgery (FESS).
To assess the role of allergy in the evolution after FESS of patients presenting with the diagnosis of NP.
This was a prospective study of 63 consecutive patients with NP (57% males, mean age 45.8 years), who were analyzed to detect whether the results of a surgical treatment of NP were influenced by the presence of positive allergic tests (Phadiatop). Three nasal criteria were scored: nasal obstruction, posterior rhinorrhea, and the loss of smell. The frequency of asthma was evaluated. Medical treatment of NP after FESS consisted of washing of the nasal cavities, steroid spray, and oral steroid administration. The amount of consumption of steroids (prednisolone and beclomethasone) was studied.
Decrease of all nasal symptoms was not statistically different in the two groups of patients with and without allergy. Cumulative consumption of prednisolone and beclomethasone after surgery was similar in the two groups.
变应性对功能性鼻内镜鼻窦手术(FESS)后鼻息肉(NP)患者的症状及类固醇药物(口服和局部)使用量无影响。
评估变应性在诊断为NP的患者FESS术后病情演变中的作用。
这是一项对63例连续的NP患者(57%为男性,平均年龄45.8岁)进行的前瞻性研究,分析NP手术治疗结果是否受变应性检测阳性(变应原筛查)的影响。对三个鼻部标准进行评分:鼻塞、后鼻漏和嗅觉丧失。评估哮喘的发生率。FESS术后NP的药物治疗包括鼻腔冲洗、类固醇喷雾和口服类固醇给药。研究类固醇(泼尼松龙和倍氯米松)的使用量。
有和没有变应性的两组患者所有鼻部症状的减轻在统计学上无差异。两组术后泼尼松龙和倍氯米松的累积使用量相似。