Sazgar Amir Arvin, Akrami Kamyar, Akrmi Shahram, Mehdizadeh Jalal, Fezi Azar
Department of Otolaryngology, Head and Neck Surgery, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Acta Otolaryngol. 2008 Feb;128(2):177-80. doi: 10.1080/00016480701477628.
The vestibular area is closer than the auditory region to nucleus ambiguus. If a 'shared' lesion involves regions of adjacent nuclei of the brainstem in patients with spasmodic dysphonia then vestibular area involvement is more possible than that of the auditory region.
The authors hypothesize that lower brainstem lesions and involvement of descending pathways of the spinal tract may be the site of lesion in patients with spasmodic dysphonia.
Ten patients with spasmodic dysphonia were tested using the auditory brainstem response (ABR) and vestibular evoked myogenic potentials (VEMPs).
No ABR abnormalities were found in right ears. Results of ABR on the left ear showed that one patient had abnormal ABR. This patient had severe sensorineural hearing loss on the left side. VEMPs displayed normal response in two patients bilaterally. First positive (p13) and second negative (n23) waves of VEMP could not be recorded in three cases unilaterally and in five patients bilaterally.
前庭区比听觉区更靠近疑核。在痉挛性发声障碍患者中,如果“共享”病变累及脑干相邻核团区域,那么前庭区受累的可能性比听觉区更大。
作者推测,痉挛性发声障碍患者的病变部位可能是脑桥下部病变以及脊髓束下行通路受累。
对10例痉挛性发声障碍患者进行了听性脑干反应(ABR)和前庭诱发肌源性电位(VEMP)测试。
右耳未发现ABR异常。左耳ABR结果显示,1例患者ABR异常。该患者左侧有严重的感音神经性听力损失。VEMP在2例患者双侧显示正常反应。在3例患者单侧以及5例患者双侧无法记录到VEMP的第一正向波(p13)和第二负向波(n23)。