Middleton M L, Wilson K M, Keith R W
Department of Otolaryngology, University of Cincinnati Medical Center, OH 45267-0528, USA.
Ear Nose Throat J. 1997 Oct;76(10):710-5.
Spasmodic dysphonia is a focal laryngeal dystonia characterized by inappropriate contractions of the intrinsic laryngeal musculature. The prevalence of associated neurological findings has led to detailed investigation of the central nervous system. Previous research revealed latency abnormalities in patients' auditory brainstem responses. The present study further investigated central auditory findings in patients with spasmodic dysphonia, including brainstem and cortical function. Fourteen normal-hearing patients with spasmodic dysphonia were tested using the auditory brainstem response (ABR) and SCAN-A test of central auditory processing. The ABR estimated brainstem transmission time and evaluated auditory pathway integrity at a high stimulus rate. SCAN-A assessed the auditory cerebral cortex. Implications of these findings are discussed. We found no ABR abnormalities in subjects with spasmodic dysphonia. Positive SCAN-A findings were negligible. The ABR findings contradict previous reports.
痉挛性发声障碍是一种局限性喉肌张力障碍，其特征为喉内肌出现不适当的收缩。相关神经学表现的患病率促使人们对中枢神经系统进行详细研究。先前的研究揭示了患者听觉脑干反应的潜伏期异常。本研究进一步调查了痉挛性发声障碍患者的中枢听觉表现，包括脑干和皮层功能。对14名患有痉挛性发声障碍的听力正常患者进行了听觉脑干反应（ABR）测试和中枢听觉处理的SCAN - A测试。ABR以高刺激率估计脑干传导时间并评估听觉通路的完整性。SCAN - A评估听觉大脑皮层。讨论了这些发现的意义。我们发现痉挛性发声障碍患者的ABR没有异常。SCAN - A的阳性结果可以忽略不计。ABR的结果与先前的报告相矛盾。
