Marioni Gino, Rinaldi Roberto, Staffieri Claudia, Marchese-Ragona Rosario, Saia Giorgia, Stramare Roberto, Bertolin Andy, Dal Borgo Roberto, Ragno Fabrizio, Staffieri Alberto
Department of Medical and Surgical Specialties, Section of Otolaryngology, University of Padova, Padova, Italy.
Acta Otolaryngol. 2008 Feb;128(2):201-6. doi: 10.1080/00016480701387157.
Diagnostic work-up should include contrast-enhanced computed tomography (CT) and mandible orthopantogram. When a dental origin of deep neck infection is suspected, the intravenous antibiotic regimen has to be active against gram-positive bacteria, both aerobes and anaerobes. Surgical exploration and drainage may be mandatory at presentation, or in cases not responding to medical therapy within the first 24 h.
Deep neck infections are still associated with significant morbidity and mortality rates when complications occur. Despite worldwide improvement in dental care and oral hygiene, a significant prevalence of deep neck infections caused by dental infections has been described recently (> 40%).
We analysed retrospectively 85 cases of deep neck infection with dental origin out of 206 consecutive cases of deep neck infection diagnosed in our institution between 2000 and 2006.
The most frequent dental source was a periapical infection of the first mandibular molar, followed by second and third molar, respectively. Submandibular space infection involvement was diagnosed in 73 of 85 patients (85.9%), masticatory space infection in 28 (32.9%); in 56 patients (65.9%) the infection involved more than one space. Twenty-four patients (28.2%) were treated only with intravenous antibiotic therapy; 61 patients (71.8%) required both medical and surgical procedures.
诊断检查应包括增强计算机断层扫描(CT)和下颌全景片。当怀疑深部颈部感染源自牙齿时,静脉用抗生素方案必须对革兰氏阳性菌(需氧菌和厌氧菌)有效。在就诊时,或在最初24小时内对药物治疗无反应的病例中,可能必须进行手术探查和引流。
深部颈部感染出现并发症时仍伴有显著的发病率和死亡率。尽管全球范围内牙科护理和口腔卫生有所改善,但最近有报道称,由牙科感染引起的深部颈部感染患病率仍很高(>40%)。
我们回顾性分析了2000年至2006年期间在本机构诊断的206例连续性深部颈部感染病例中的85例源自牙齿的深部颈部感染病例。
最常见的牙齿感染源是下颌第一磨牙根尖周感染,其次分别是第二和第三磨牙。85例患者中有73例(85.9%)被诊断为下颌下间隙感染,28例(32.9%)为咀嚼肌间隙感染;56例患者(65.9%)的感染累及多个间隙。24例患者(28.2%)仅接受静脉抗生素治疗;61例患者(71.8%)需要药物和手术治疗。