Kim So Young, Park Il Hwan, Byun Chun Sung, Choi Hyo Geun, Kwon Mi Jung, Kim Ji Hee, Kim Joo-Hee, Kim Chang Wan
Department of Anatomy and Cell Biology, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.
Department of Cardiovascular and Thoracic Surgery, Yonsei University Wonju College of Medicine, Wonju 26426, Republic of Korea.
J Clin Med. 2024 Apr 9;13(8):2166. doi: 10.3390/jcm13082166.
Odontogenic infection is one of the main etiologies of deep neck infection (DNI). However, the relationship between chronic periodontitis (CP) and the incidence of DNI has not been examined. This study aimed to evaluate the incidence of DNI and peritonsillar abscess (PTA) after CP. The Korean National Health Insurance Service-National Sample Cohort 2002-2019 was used. In Study I, 4585 PTA patients were matched with 19,340 control I participants. A previous history of CP for 1 year was collected, and the odds ratios (ORs) of CP for PTA were analyzed using conditional logistic regression. In Study II, 46,293 DNI patients and 185,172 control II participants were matched. A previous history of CP for 1 year was collected, and conditional logistic regression was conducted for the ORs of CP for DNI. Secondary analyses were conducted in demographic, socioeconomic, and comorbidity subgroups. In Study I, a history of CP was not related to the incidence of PTA (adjusted OR = 1.28, 95% confidence interval [CI] = 0.91-1.81). In Study II, the incidence of DNI was greater in participants with a history of CP (adjusted OR = 1.55, 95% CI = 1.41-1.71). The relationship between CP history and DNI was greater in groups with young, male, low-income, and rural residents. : A prior history of CP was associated with a high incidence of DNI in the general population of Korea. Patients with CP need to be managed for the potential risk of DNI.
牙源性感染是深部颈部感染（DNI）的主要病因之一。然而，慢性牙周炎（CP）与DNI发病率之间的关系尚未得到研究。本研究旨在评估CP后DNI和扁桃体周围脓肿（PTA）的发病率。使用了韩国国民健康保险服务-全国样本队列2002-2019。在研究I中，4585例PTA患者与19340例对照I参与者进行匹配。收集了1年的CP既往史，并使用条件逻辑回归分析CP对PTA的比值比（OR）。在研究II中，46293例DNI患者与185172例对照II参与者进行匹配。收集了1年的CP既往史，并对CP对DNI的OR进行条件逻辑回归分析。在人口统计学、社会经济和合并症亚组中进行了二次分析。在研究I中，CP病史与PTA发病率无关（调整后的OR = 1.28，95%置信区间[CI] = 0.91-1.81）。在研究II中，有CP病史的参与者中DNI发病率更高（调整后的OR = 1.55，95%CI = 1.41-1.71）。在年轻、男性、低收入和农村居民组中，CP病史与DNI之间的关系更大。：在韩国普通人群中，CP既往史与DNI的高发病率相关。CP患者需要针对DNI的潜在风险进行管理。
