Boreu Quintí Foguet, de Tuero Gabriel Coll, Rodríguez-Poncelas Antonio, Albertos Maria Sanmartín, Zafra Marc Saez, Radó Maria Antonia Barceló
Campdevànol Hospital, Campdevànol, Girona, Spain.
Blood Press. 2007;16(6):354-61. doi: 10.1080/08037050701538089.
The aim of this study was to determine the proportion of isolated clinical hypertension (ICH) in newly diagnosed hypertensive patients, and to compare the incidence of target organ damage (TOD) in ICH and sustained hypertension patients. Participants. In a multi-centre study involving 14 primary care centres in Girona, Spain, 140 researchers recruited 214 newly diagnosed hypertensive patients 15-75 years of age, without history of cardiovascular events. Period of study. 2004-6. Method. Self-blood pressure monitoring (SBPM) and ambulatory blood pressure monitoring (ABPM). Evaluation. Anamnesis including blood pressure, physical examination and analysis (creatinine, albumin/creatinine index), electrocardiogram (left ventricular hypertrophy) and retinography (fundus damage). Results. In 129 (60.3%) subjects with sustained hypertension and 85 (39.7%) with ICH, no significant differences were found relative to gender, age, body mass index or blood pressure (155/90 vs 154/90 mmHg, respectively). Cholesterol levels were significant differences between both groups (5.97 mmol/l in sustained hypertension vs 5.64 mmol/l in ICH, p = 0.029). The proportion of ICH was approximately 40%. TOD incidence in sustained hypertensives was similar to that of ICH patients.
本研究的目的是确定新诊断高血压患者中孤立性临床高血压(ICH)的比例,并比较ICH患者和持续性高血压患者靶器官损害(TOD)的发生率。参与者。在一项涉及西班牙赫罗纳14个初级保健中心的多中心研究中,140名研究人员招募了214名年龄在15至75岁之间、无心血管事件病史的新诊断高血压患者。研究期间。2004年至2006年。方法。自我血压监测(SBPM)和动态血压监测(ABPM)。评估。问诊包括血压、体格检查和分析(肌酐、白蛋白/肌酐指数)、心电图(左心室肥厚)和视网膜造影(眼底损害)。结果。在129名(60.3%)持续性高血压患者和85名(39.7%)ICH患者中,在性别、年龄、体重指数或血压方面(分别为155/90 mmHg和154/90 mmHg)未发现显著差异。两组之间的胆固醇水平存在显著差异(持续性高血压患者为5.97 mmol/l,ICH患者为5.64 mmol/l,p = 0.029)。ICH的比例约为40%。持续性高血压患者的TOD发生率与ICH患者相似。