Department of Psychology, University of Tulsa, Tulsa, OK 74104, USA.
J Clin Exp Neuropsychol. 2008 Jan;30(1):63-9. doi: 10.1080/13803390601186957. Epub 2007 Mar 12.
Although memory impairment is common in people with multiple sclerosis (MS), few interventions have been tested to remediate forgetfulness in MS. Chiaravalloti and DeLuca (2002) examined the memory benefit of self-generated encoding over didactic presentation in people with MS and a control group. They found that self-generated encoding enhanced memory of MS patients and a control group alike. The present study extended this finding by examining self-generated encoding in memory-impaired MS patients as well. A control group and MS patients with and without memory impairment learned word-pairs that were either self-generated or didactically presented. All groups remembered more self-generated words than those that were read aloud, and severity of memory impairment failed to moderate this memory benefit. Implications of these findings for cognitive rehabilitation and the nature of memory impairment in MS are discussed.
尽管多发性硬化症（MS）患者常伴有记忆障碍，但针对该障碍的治疗方法却寥寥无几。Chiaravalloti 和 DeLuca（2002 年）曾研究过自我生成编码对 MS 患者和对照组遗忘的记忆改善作用。他们发现，自我生成编码可增强 MS 患者和对照组的记忆力。本研究通过对记忆受损的 MS 患者的自我生成编码进行检验，进一步证实了这一发现。对照组和有或无记忆障碍的 MS 患者学习了自我生成或讲授呈现的单词对。所有组记住的自我生成单词都多于大声朗读的单词，且记忆障碍的严重程度并未影响这种记忆益处。讨论了这些发现对认知康复和 MS 中记忆障碍本质的意义。
