新型微型体外循环系统（ECC.O）在冠状动脉手术中是一项安全技术。
New mini-extracorporeal circulation system (ECC.O) is a safe technique in coronary surgery.
作者信息
Valtonen Mika, Vähäsilta Tommi, Kaila-Keinänen Tessa, Kuttila Kari
机构信息
Department of Anaesthesia and Intensive Care, Turku University Hospital, Finland.
出版信息
Scand Cardiovasc J. 2007 Oct;41(5):345-50. doi: 10.1080/14017430701446933.
OBJECTIVES
Cardiopulmonary bypass (CPB) is known to cause the systemic inflammatory reaction after cardiac surgery. New coated and closed loop circuit systems may reduce this inflammation response and improve the surgical outcome. This study was designed to evaluate the safety and efficacy of the mini-extracorporeal circulation system (ECC.O) in CABG patients.
DESIGN
Forty patients undergoing elective coronary surgery were randomized into two groups, the ECC.O group and the standard CPB group. Routine hemodynamic monitoring and biochemical measurements were registered according to the hospital practice.
RESULTS
The clinical outcome of the patients was similar in both groups. There were no significant differences between the groups in the duration of intubation following surgery, the length of intensive care unit-stay or the total hospital stay. The haemoglobin level was significantly higher (p=0.0069) during and after the perfusion in the ECC.O group.
CONCLUSIONS
The ECC.O system can be safely used in CABG patients and it maintains haemoglobin level better than conventional CPB.
目的
已知体外循环（CPB）会在心脏手术后引发全身炎症反应。新型涂层和闭环循环系统可能会减轻这种炎症反应并改善手术效果。本研究旨在评估迷你体外循环系统（ECC.O）在冠状动脉旁路移植术（CABG）患者中的安全性和有效性。
设计
40例接受择期冠状动脉手术的患者被随机分为两组，即ECC.O组和标准CPB组。根据医院常规做法记录常规血流动力学监测和生化指标测量结果。
结果
两组患者的临床结局相似。两组在术后插管持续时间、重症监护病房停留时间或总住院时间方面无显著差异。ECC.O组在灌注期间及之后血红蛋白水平显著更高（p = 0.0069）。
结论
ECC.O系统可安全用于CABG患者，并且其维持血红蛋白水平的效果优于传统CPB。
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