Agarwal M K
Experientia. 1976 Apr 15;32(4):531-3. doi: 10.1007/BF01920840.
It is shown that cytosol preparations bound with various concentrations of a steroid are necessary to reveal physicochemically distinct, heterogeneous and polymorphic receptors present in the hormone specific target organ, that these cannot be fully appreciated in one-shot experiments at suboptimal steroids levels, and that they escape detection by equilibrium binding and Scatchard analysis alone.
结果表明，与不同浓度类固醇结合的胞质溶胶制剂对于揭示激素特异性靶器官中存在的物理化学性质不同、异质性和多态性的受体是必要的，这些受体在次优类固醇水平的一次性实验中无法得到充分认识，并且仅通过平衡结合和斯卡查德分析无法检测到它们。
