Haglund Bengt, Eliasson Mats, Stenbeck Magnus, Rosén Måns
Centre for Epidemiology, Swedish National Board of Health and Welfare, Stockholm, Sweden.
Scand J Public Health. 2007;35(6):618-22. doi: 10.1080/14034940701436949.
The potential risks of Swedish moist snuff (snus) are debated and studies have shown diverging results.
The aim of this study is to investigate whether there is any excess risk of ischaemic heart disease (IHD) and stroke from snuff use.
The Swedish Survey of Living Conditions from 1988-89 was record-linked to the Swedish Cause of Death Register and the Swedish Hospital Discharge Register to investigate excess mortality and hospitalization from IHD and stroke. A Poisson regression model was used and incidence rate ratios (IRRs) for snuff and smoking were calculated controlling for age, physical activity, self-reported health, number of longstanding illnesses, residential area, and socioeconomic position.
Among snuff users there were no excess risks of mortality or hospitalization from IHD (IRR 0.8; 0.5-1.2,) or stroke (IRR 1.1; 0.7-1.8), but, as expected, clear excess risks were found for smokers (IRR 1.7; 1.4-2.1 for IHD, and IRR 1.4; 1.0-1.9 for stroke).
This study has not shown any excess risk among users of snuff for IHD or stroke. If there is a risk associated with snuff it is evidently much lower than those associated with smoking.
瑞典湿鼻烟的潜在风险存在争议,研究结果也各不相同。
本研究旨在调查使用鼻烟是否会增加患缺血性心脏病(IHD)和中风的风险。
1988 - 1989年瑞典生活条件调查与瑞典死亡原因登记册和瑞典医院出院登记册进行记录关联,以调查IHD和中风导致的超额死亡率和住院率。使用泊松回归模型,计算鼻烟和吸烟的发病率比(IRR),并对年龄、身体活动、自我报告的健康状况、长期疾病数量、居住地区和社会经济地位进行控制。
在鼻烟使用者中,IHD(IRR 0.8;0.5 - 1.2)或中风(IRR 1.1;0.7 - 1.8)导致的死亡率或住院率没有额外风险,但正如预期的那样,吸烟者存在明显的额外风险(IHD的IRR为1.7;1.4 - 2.1,中风的IRR为1.4;1.0 - 1.9)。
本研究未显示鼻烟使用者患IHD或中风的额外风险。如果鼻烟存在相关风险,显然远低于与吸烟相关的风险。