Gołkowski F, Trofimiuk M, Czepko R, Buziak-Bereza M, Lopatka P, Adamek D, Bałdys-Waligórska A, Huszno B
Department of Endocrinology, Jagiellonian University, Collegium Medicum, Kopernika 17, 31-501 Krakow, Poland.
Exp Clin Endocrinol Diabetes. 2007 Sep;115(8):537-40. doi: 10.1055/s-2007-981456.
Pituitary metastases, though very uncommon, may cause endocrine and neurosurgical problems. The clinical manifestation of such metastases is highly variable. Most of the metastatic pituitary tumours are oligosymptomatic. We report two cases of metastatic pituitary lesions. The first patient, a 52-year old female, with metastatic breast cancer, developed symptomatic anterior pituitary insufficiency. The second patient, a 46-years old female presented with signs and symptoms of pituitary apoplexy and visual impairment due to metastasis from renal cancer. None of them was diagnosed with diabetes insipidus, the most common manifestation related to pituitary metastatic mass.
垂体转移瘤虽然非常罕见,但可能导致内分泌和神经外科问题。此类转移瘤的临床表现高度多变。大多数转移性垂体肿瘤症状较少。我们报告两例垂体转移病变病例。首例患者为一名52岁女性,患有转移性乳腺癌,出现有症状的垂体前叶功能减退。第二例患者是一名46岁女性,因肾癌转移出现垂体卒中体征和症状以及视力损害。她们均未被诊断为尿崩症,而尿崩症是与垂体转移瘤相关的最常见表现。