Petrović Dejan, Stojimirović Biljana
Klinika za urologiju i nefrologiju, Odeljenje hemodijalize, Klinicki centar Kragujevac.
Med Pregl. 2007 Mar-Apr;60(3-4):183-6. doi: 10.2298/mpns0704183p.
Vascular access blood flow rate of 100-350 cm/s and between 500 and 1000 ml/min, points to normal vascular access function and adequate hemodialysis. High blood flow through the arteriovenus fistula overloads the left ventricle inducing left ventricular remodiling.
The aim of the study was to establish the degree of correlation between blood flow through the vascular access for hemodialysis and echocardiographic parameters for the assessment of left ventricular hypertrophy and left ventricular dilatation and left ventricular function. The research included 115 patients (M:F 71:44), average age 53.30+/-12.17 years, average length of dialysis 4.51 +/- 4.01 years and average Kt/Vsp index 1.17+/-0.23.
The average blood flow through the vascular access for hemodialysis was 662.27+/-301.59 ml/min. EDDLV 54.52+/-6.42 mm, and EDVi 100.80+/-34.62 ml/m2. There is a statistically significant positive correlation between blood flow through vascular access for hemodialysis and EDDLV and EDVi.
High blood flow through the vascular access for hemodialysis is an independent risk factor for the development of cardiovascular complications in patients on hemodialysis.
血管通路血流量为100 - 350厘米/秒，500至1000毫升/分钟，表明血管通路功能正常且血液透析充分。通过动静脉内瘘的高血流量会使左心室负荷过重，导致左心室重构。
本研究的目的是确定血液透析血管通路血流量与评估左心室肥厚、左心室扩张和左心室功能的超声心动图参数之间的相关程度。该研究纳入了115例患者（男:女为71:44），平均年龄53.30±12.17岁，平均透析时长4.51±4.01年，平均Kt/Vsp指数为1.17±0.23。
血液透析血管通路的平均血流量为662.27±301.59毫升/分钟。左心室舒张末期内径（EDDLV）为54.52±6.42毫米，左心室舒张末期容积指数（EDVi）为100.80±34.62毫升/平方米。血液透析血管通路血流量与EDDLV和EDVi之间存在统计学上显著的正相关。
血液透析血管通路的高血流量是血液透析患者发生心血管并发症的独立危险因素。
