Kisa Cebrail, Aydemir Ciğdem, Kurt Aydin, Gülen Sema, Göka Erol
Ankara Numune Eğitim ve Araştirma Hastanesi 1, Psikiyatri KI., Ankara.
Turk Psikiyatri Derg. 2007 Fall;18(3):223-30.
This research compared the demographic features, presence of confusion, and long-term follow-up results of women with postpartum psychosis to control subjects.
The study included 23 patients with symptoms that emerged in the six-month period after delivery who were followed-up between 1998 and 2006. The control group consisted of 25 age- and education level-matched female patients experiencing their first psychotic episode. Data were collected with a sociodemographic questionnaire, the Clinical Global Impression Scale, and the Delirium Rating Scale. Final diagnoses were made according to DSM-IV.
Among the postpartum women, 73.9% developed psychosis during their first parturition. The postpartum psychosis and control groups were followed-up for 4.00 +/- 1.62 (range: 2-6) and 3.96 +/- 1.24 (range: 2-6) years, respectively. During the follow-up period, 21.7% of the postpartum patients developed a mood disorder, and 77.9% developed schizophrenia and other psychotic disorders. Among those in the control group, 32.0% were diagnosed with a mood disorder and 68.0% with schizophrenia and other psychotic disorders. The distribution of final diagnoses in the 2 groups were similar. Patients with postpartum psychosis experienced more confusion than the control subjects. During the follow-up period, 65.2% of the patients with postpartum psychosis and 72% of the control patients had recurrence.
The course of postpartum psychosis was similar to DSM-IV diagnostic criteria, except for the presence of confusion. During the follow-up period, most of the patients in both groups were diagnosed with schizophrenia and other psychotic disorders. This result indicated that there is no need for other diagnostic criteria for postpartum psychosis other than those presently contained in DSM-IV.
本研究比较了产后精神病妇女与对照对象的人口统计学特征、意识模糊情况及长期随访结果。
该研究纳入了23例在产后6个月内出现症状且于1998年至2006年期间接受随访的患者。对照组由25例年龄和教育水平相匹配的首次发生精神病性发作的女性患者组成。通过社会人口学问卷、临床总体印象量表和谵妄评定量表收集数据。最终诊断依据《精神疾病诊断与统计手册》第四版(DSM-IV)做出。
在产后妇女中,73.9%在首次分娩期间患精神病。产后精神病组和对照组的随访时间分别为4.00±1.62年(范围:2 - 6年)和3.96±1.24年(范围:2 - 6年)。在随访期间,21.7%的产后患者患心境障碍,77.9%患精神分裂症及其他精神病性障碍。对照组中,32.0%被诊断为心境障碍,68.0%被诊断为精神分裂症及其他精神病性障碍。两组最终诊断的分布相似。产后精神病患者比对照对象经历更多的意识模糊。在随访期间,65.2% 的产后精神病患者和72%的对照患者复发。
产后精神病病程与DSM-IV诊断标准相似,意识模糊情况除外。在随访期间,两组中的大多数患者被诊断为精神分裂症及其他精神病性障碍。这一结果表明,除了目前DSM-IV中包含的标准外,无需其他产后精神病诊断标准。