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一种通过正中胸骨切开术进行心脏手术疼痛管理的新方法:双侧单次椎旁阻滞。

A novel approach for pain management in cardiac surgery via median sternotomy: bilateral single-shot paravertebral blocks.

作者信息

Olivier Jean-François, Bracco David, Nguyen Philippe, Le Nhien, Noiseux Nicolas, Hemmerling Thomas

机构信息

Department of Anesthesiology, McGill University Health Center, Montréal, Québec, Canada.

出版信息

Heart Surg Forum. 2007;10(5):E357-62. doi: 10.1532/HSF98.20071082.

Abstract

Regional analgesia has entered cardiac anesthesia in the form of spinal or epidural analgesia. However, the risk of spinal or epidural hematoma is a constant worry. Alternative regional techniques might be applicable in cardiac surgery. The purpose of this study is to present a novel technique of bilateral single-shot paravertebral blocks (BSS-PVB) for cardiac surgery via median sternotomy and compare its efficacy versus high thoracic epidural analgesia (TEA). Fifty-two patients were compared in this prospective cohort audit. In 26 patients, cardiac surgery was performed using low-dose fentanyl/BSS-PVB (bilateral blocks of 3 mL bupivacaine 0.5% each, T1-7) and general anesthesia; in another 26 patients, TEA (bupivacaine 0.125% at 10 mL/hour) and general anesthesia were used. Patients were assigned to cohorts according to their preoperative data and types of surgery. All patient data are shown as mean +/- SD; pain scores were compared between groups using the t test immediately, 6 hours, and 24 hours after surgery (P < .05). In the BSS-PVB-group (19 men, 7 women), mean age was 65 +/- 11 years, weight 74 +/- 16 kg, ejection fraction 59% +/- 12%, and duration of surgery 130 +/- 27 minutes; in the TEA-group (17 men, 9 women), mean age was 63 +/- 10 years, weight 75 +/- 16 kg, ejection fraction 58% +/- 12%, and duration of surgery 113 +/- 27 minutes. These data and preoperative comorbidity variables were not significantly different between the two groups. In each group, 18 patients underwent off-pump coronary artery bypass grafting, 3 on-pump and 5 mitral valve replacements. All patients were successfully immediately extubated. Postoperative pain scores were at any point significantly lower with TEA, immediately at 2.4 +/- 2.2 versus 3.7 +/- 2.6, at 6 hours at 1.1 +/- 1.5 versus 2.4 +/- 1.8, and at 24 hours at 1.0 +/- 1.4 versus 2.3 +/- 1.6 (0 = no pain, 10 = maximum pain). There was no complications related to epidural catheter placement or BSS-PVB. Using both techniques, immediate extubation after cardiac surgery is feasible; TEA provides better pain relief after cardiac surgery than BSS-PVB.

摘要

区域镇痛已以脊髓或硬膜外镇痛的形式应用于心脏麻醉。然而,脊髓或硬膜外血肿的风险一直令人担忧。其他区域技术可能适用于心脏手术。本研究的目的是介绍一种用于正中开胸心脏手术的双侧单次椎旁阻滞(BSS-PVB)新技术,并比较其与高位胸椎硬膜外镇痛(TEA)的效果。在这项前瞻性队列审计中对52例患者进行了比较。26例患者在心脏手术中使用低剂量芬太尼/BSS-PVB(双侧各3 mL 0.5%布比卡因,T1-7)和全身麻醉;另外26例患者使用TEA(0.125%布比卡因,10 mL/小时)和全身麻醉。根据患者的术前数据和手术类型将其分配到不同队列。所有患者数据均以均值±标准差表示;术后立即、术后6小时和24小时使用t检验比较两组的疼痛评分(P < 0.05)。在BSS-PVB组(19例男性,7例女性)中,平均年龄为65±11岁,体重74±16 kg,射血分数59%±12%,手术时间130±27分钟;在TEA组(17例男性,9例女性)中,平均年龄为63±10岁,体重75±16 kg,射血分数58%±12%,手术时间113±27分钟。两组之间的这些数据和术前合并症变量无显著差异。每组中,18例患者接受非体外循环冠状动脉搭桥术,3例接受体外循环手术,5例接受二尖瓣置换术。所有患者均成功立即拔管。TEA组术后任何时间的疼痛评分均显著低于BSS-PVB组,术后立即为2.4±2.2 vs 3.7±2.6,术后6小时为1.1±1.5 vs 2.4±1.8,术后24小时为1.0±1.4 vs 2.3±1.6(0 = 无疼痛,10 = 最大疼痛)。未发生与硬膜外导管置入或BSS-PVB相关的并发症。使用这两种技术,心脏手术后立即拔管是可行的;TEA在心脏手术后提供的疼痛缓解效果优于BSS-PVB。

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