Wilson D J, Norman B B, Hird D W, Wilson C B, Oliver M N
Department of Epidemiology and Preventive Medicine, School of Veterinary Medicine, University of California, Davis 95616.
Am J Vet Res. 1991 Nov;52(11):1866-70.
Five groups of Hereford steers were monitored for 293 days. One group of 3 was not given selenium supplementation; the other 4 groups of 3 steers each were given 2, 4, 6, or 8 reticulorumen selenium pellets. Health, body weight, and blood selenium concentration were monitored during the study. At the finish, steers were slaughtered, and various tissues from the carcasses were analyzed for selenium content. Initial blood selenium concentration did not differ significantly among groups. However, significant (alpha = 0.01) difference among means was detected during the early period of rapid increase in blood selenium concentration in steers of supplemented groups. Means of maximal blood selenium concentration also differed among groups; however, even the highest value, 0.253 micrograms/g, was lower than the 3 micrograms/ml reported in chronic clinical cases of toxicosis in the literature. Carcass analysis indicated significant (alpha = 0.05) differences in selenium concentrations among treatment groups for almost all tissues tested. Only kidney samples (7.9 micrograms/g) from steers of the 8-pellet treatment group exceeded published normal values (7.6 micrograms/g). Health variables for most dates were not significantly different among groups, and selenium toxicosis was not evident in any steer. Analysis did not indicate risk to human beings consuming tissues from these steers.
对五组赫里福德阉牛进行了293天的监测。一组3头牛未补充硒；其他四组每组3头牛分别投喂2、4、6或8个网胃硒丸。研究期间监测了健康状况、体重和血液硒浓度。研究结束时，宰杀阉牛，并分析胴体的各种组织中的硒含量。各组的初始血液硒浓度无显著差异。然而，在补充组阉牛血液硒浓度快速上升的早期阶段，检测到各组均值存在显著差异（α = 0.01）。各组的最大血液硒浓度均值也有所不同；然而，即使是最高值0.253微克/克，也低于文献中慢性中毒临床病例报告的3微克/毫升。胴体分析表明，几乎所有测试组织的处理组之间硒浓度存在显著差异（α = 0.05）。只有8丸处理组阉牛的肾脏样本（7.9微克/克）超过了已公布的正常值（7.6微克/克）。大多数日期的健康变量在各组之间无显著差异，且任何阉牛均未出现明显的硒中毒症状。分析表明，食用这些阉牛组织对人类没有风险。
